TY - JOUR
AU - MUSO, ERI
AB -  PURPOSE The pathological role of obesity in the progression of glomerular lesion has been suggested in obesity‐related nephropathy, but has rarely been studied in primary glomerular diseases. The purpose of this study is to examine the clinicopathological influence of excessive body weight in IgA nephropathy. METHODS Sixty‐eight patients with renal biopsy‐proven IgA nephropathy in our institute from October 2000 to November 2003 were retrospectively divided into two groups according to body mass index (BMI); non‐obese group (group N) with BMI < 25 kg/m 2 and obese group (group O) with BMI ≥ 25 kg/m 2 . Patients with diabetes mellitus or autoimmune diseases were excluded. For all patients, we collected the following data at the period of renal biopsy: (1) physiological findings: gender, age, height, body weight, the frequency of hypertension; (2) laboratory findings: 24‐h protein excretion, creatinine clearance adjusted for body surface area, haematuria (red blood cell counts per high‐power field in the urine sediment), serum creatinine, blood urea nitrogen, serum albumin, serum immunoglobulin A (IgA), total cholesterol; (3) pathological findings: light microscopical examination, electron microscopical examination of glomerular basement membrane (GBM) thickness, immunohistochemical examination of alpha‐smooth muscle actin (alpha SMA). Hemoglobin A1c (HbA1c), plasma renin activity 
TI - Clinicopathological influence of excess body weight in IgA nephropathy: Comparative study of 68 patients
JO - Nephrology
DO - 10.1111/j.1440-1797.2005.00518.x
DA - 2005-12-01
UR - https://www.deepdyve.com/lp/wiley/clinicopathological-influence-of-excess-body-weight-in-iga-nephropathy-3VkRaEdqUh
SP - A435
EP - A436
VL - 10
IS - 
DP - DeepDyve
ER -