TY - JOUR
AU - Morrill, Lohn C.
AB - THE JOURNAL OF INFECTIOUS DISEASES· VOL. 155, NO.4. APRIL 1987 Levels of Interferon in the Plasma and Cerebrospinal Fluid of Patients with Acute Japanese Encephalitis pooled, and stored at -70 C in HBSS with 2% heat­ The arthropod-borne flaviviruses, a group that includes Japanese encephalitis virus (JEV), St. Louis encephalitis inactivated fetal bovine serum and 1% penicillin/strep­ virus, and tick-borne encephalitis virus, are major causes tomycin. The virus pool was titrated by plaque formation of acute viral encephalitis in most regions of the world. in Vero cells. Interferon assay. Human leukocyte interferon was as­ In the past decade. epidemics of acute viral encephalitis attributable to JEV have occurred throughout most of Asia sayed in a micro, dye-uptake. CPE-inhibition assay [6, 7]. (from India to Korea). with case-fatality rates characteristi­ Serial twofold dilutions of human serum or CSF were made in 96-well microtiter plates. Each sample was run in dupli­ cally around 30070 [1]. There are no specific antiviral agents with proven efficacy for treating acute Japanese encepha­ cate wells. Approximately 3 x 10 freshly trypsinized cells litis (JE); treatment is entirely supportive. were introduced into each well. and the plates were in­ Interferon has been shown to be active 
TI - Levels of Interferon in the Plasma and Cerebrospinal Fluid of Patients with Acute Japanese Encephalitis
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/155.4.797
DA - 1987-04-01
UR - https://www.deepdyve.com/lp/oxford-university-press/levels-of-interferon-in-the-plasma-and-cerebrospinal-fluid-of-patients-3N4GbzMjp9
SP - 797
EP - 799
VL - 155
IS - 4
DP - DeepDyve
ER -