TY - JOUR
AU - Sims, P.
AB - Benz[a]anthracene-10,11-diol, a major metabolite of benz[a]anthracene, is metabolized by a rat-liver microsomal system to form anti-BA-10,11-diol 8, 9-oxide (t-10,r-11-dihydroxy-t-8,9-oxy-8,9, 10,11-tetrahydrobenz[a]anthracene) and, to a lesser extent, syn-BA-10,11-diol 8,9-oxide (t-10 r-11-dihydroxy-c-8,9-oxy-8,9,10,11-tetrahydrobenz[a]anthracene). However, when benz[a]anthracene is incubated with DNA in a rat-liver microsomal system, anti-BA-10,11-diol 8,9-oxide does not contribute to the covalent binding of this hydrocarbon to DNA
TI - The metabolism of the 10,11-dihydrodiol of benz[a]-anthracene to a vicinal diol-epoxide that is not involved in metabolic activation
JF - Carcinogenesis
DO - 10.1093/carcin/1.11.937
DA - 1980-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-metabolism-of-the-10-11-dihydrodiol-of-benz-a-anthracene-to-a-3F52MUzzmE
SP - 937
EP - 943
VL - 1
IS - 11
DP - DeepDyve
ER -