TY - JOUR
AU1 - KOBAYASHI,, Yasuo
AB - Abstract A possible role of the pars intermedia of the mouse pltuitary was studied by quantitative electron microscopy after the ingestion of a low sodium diet for two weeks. An increase in the number of the renin granules in the juxtaglomerular cells from 10.8 (control) to 31.4 (2 weeks) per cell proved the brown rice to be a low sodium diet. The area of mitochondria in the section of the zona glomerulosa cells of adrenals was 0.17 μ2 (control) and 0.33 μ2 (2 weeks), suggesting a rise in the activity of mitochondria in which contained enzymes essential for aldosterone biosynthesis. The pars intermedia of the pituitary simultaneously exhibited marked changes in the fine structures under the dietary sodium restriction. The population density of secretory granules including vesicles in the pars intermedia cells was 5.7 per μ2 (control) and 2.4 per μ2 (2 weeks); and the area of Golgi region in these cells was 7.8 μ2 (control) and 10.7 μ2 (2 weeks) respectively. These results indi–cated that the release of secretory granules exceeded the increased formation of granules, and suggested that the pars intermedia hormone might have an Ultimate relation to a major pituitary factor necessary for aldosterone secretion. This content is only available as a PDF. Author notes *Present address: Department of Biology, Faculty of Science, Okayama University, Tsushima, Okayama, Japan © Oxford University Press
TI - Quantitative and Electron Microscopic Studies on the Pars Intermedia of the Hypophysis I. Dietary Effects of Brown Rice on the Kidney, Adrenal and Pituitary of C57BL/6 Mouse
JF - Journal of Electron Microscopy
DO - 10.1093/oxfordjournals.jmicro.a049910
DA - 1974-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/quantitative-and-electron-microscopic-studies-on-the-pars-intermedia-30yDDqbMTB
SP - 107
EP - 115
VL - 23
IS - 2
DP - DeepDyve
ER -