TY - JOUR
AU - Wang, Chaoli
AB - Carbon quantum dots (CQDs) are drawing tremendous attention due to their unique photoluminescence property and fascinating functions. Herein, we prepared novel CQDs functionalized with amino acids (AA-CQDs) by a one-pot hydrothermal method for selective detection of Al3+ ions and fluorescence imaging. The prepared AA-CQDs exhibit a novel triple-excitation and single-colour emission for fluorescent property. In addition, the AA-CQDs have a high absolute quantum yield (24.23%) and quantum lifetime (13.29 ns). Moreover, the AA-CQDs exhibit high selectivity and sensitivity for Al3+ by fluorescence enhancement. In pH 7.4 PBS solution, there was a good linear relation between the fluorescence intensity and the concentration of Al3+ in the range of 1–20 μmol L−1; the limit of detection (3σ) was only 0.32 μmol L−1. Furthermore, an AA-CQD probe was also utilized for detection of Al3+ in living cells based on excellent biocompatibility and endocytosis. Based on the concentration of Al3+ ions in cells and apoptosis data, there will be a quick reflect of apoptosis induced by aluminium ions via the fluorescence intensity of the AA-CQD probe. This work will set the stage for developing novel CQD-based biosensors in cell research.Graphical abstract[graphic not available: see fulltext]
TI - Amino acid–functionalized carbon quantum dots for selective detection of Al3+ ions and fluorescence imaging in living cells
JF - Analytical and Bioanalytical Chemistry
DO - 10.1007/s00216-021-03348-x
DA - 2021-04-28
UR - https://www.deepdyve.com/lp/springer-journals/amino-acid-functionalized-carbon-quantum-dots-for-selective-detection-30gxt1VIFC
SP - 3965
EP - 3974
VL - 413
IS - 15
DP - DeepDyve
ER -