TY - JOUR
AU - Koldaev, A.
AB - EXPERIMENTAL DETERMINATION OF THE EFFECTIVENESS OF HEMODIALYStS OF CERTAIN DRUGS AND TOXINS A. A. Yaroslavskii, N. N. Firsov, UDC 615.9.036.11.08:616.61-78 and A. A. Koldaev During hemodialysis with the Soviet artificial kidney apparatus, the clearance of methyl alco- hol was 150 ml/min. The clearance of ethyl alcohol was 100 ml/min, and of dichloroethane 40 ml/min. The clearance of barbital was 35 ml/min, of phenobarbital 22 ml/min, and of nem- butal 15 ml/min. The use of hemodialysis in the treatment of acute clinical poisoning is increasing year by year [1-6, 8]. However, the value of this method of treatment is mainly assessed by its clinical effect. The clear- ance of most drugs and toxic substances by the Soviet artificial kidney is not known, and it is difficult to predict the required duration of dialysis or to estimate its effectiveness correctly. The object of the investigation described below was to determine the effectiveness of hemodialysis of barbiturates, dichloroethane, and methy[ and ethyl alcohols and to establish the clearance of these sub- stances under experimental conditions as close to clinical as possible. EXPERIMENTAL METHOD AND RESULTS The substance for testing was dissolved in 2.5-5 liters blood taken from a cadaver, or in blood 
TI - Experimental determination of the effectiveness of hemodialysis of certain drugs and toxins
JF - Bulletin of Experimental Biology and Medicine
DO - 10.1007/BF00808476
DA - 2004-11-28
UR - https://www.deepdyve.com/lp/springer-journals/experimental-determination-of-the-effectiveness-of-hemodialysis-of-2nYP002DOp
SP - 384
EP - 385
VL - 71
IS - 4
DP - DeepDyve
ER -