TY - JOUR AU - Mody, Nat AB - ERNESTO B. EUSEBIO, M.D., JAMES GRAHAM, M.D., NAT MODY, M.D. Eusebio EB, Graham J, Mody N. Treatment of intractable pruri- From the Department of Surgery, Southern Illinois tus ani. Dis Colon Rectum 1990;33:770-772. University School of Medicine, Springfield Clinic, Springfield, Illinois The majority of patients with idiopathic pruritus ani respond favorably to conservative treatment. Moreover, response to spe- cific medical therapy is almost always favorable in certain der- matologic diseases such as psoriasis, mycotic dermatitis, and con- tact dermatitis. When surgery is performed for anorectal disor- fering from intractable pruritus ani who responded ders such as hemorrhoids and fistulas, or potentially malignant favorably to methylene blue treatment and were entities such as extramammary Paget's disease, the accompany- symptom free 3 to 15 months thereafter. ing pruritus ani invariably improves as well. Only patients with chronic intractable pruritus ani are included in the current study. Materials and Methods Methylene blue (methylthionine chloride) 0.5 percent is injected intracutaneously on the anodermal and perianal skin. With one For the last 9.5 years, a series of patients with in- treatment, long-term cure has been observed. [Key words: tractable pruritus ani were treated using anal and Chronic, intractable, pruritus ani; Recalcitrant anal itch, methyl- TI - Treatment of intractable pruritus ani JF - Diseases of the Colon & Rectum DO - 10.1007/BF02052324 DA - 1990-09-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/treatment-of-intractable-pruritus-ani-2O0WoHs0by SP - 770–772-770&ndash EP - ndash;772-770–772 VL - 33 IS - 9 DP - DeepDyve ER -