TY - JOUR AU - Salvesen, Bjarne AB - THE SEPARATION AND IDENTIFICATION OF SOME SYMPATHOMIMETIC AMINES BY PAPER PARTITION CHROMATOGRAPHY BY ALF WICKSTROM and BJARNE SALVESEN From the Department of Pharmaceutical Chemistry, Institute of Pharmacy, University of Oslo, Norway Received June 5, 1952 IN pharmaceutical analysis micro methods are sometimes required for the identification of sympathomimetic amines. In a previous publication1 one of the authors has reported the optical crystallographic properties of some commonly used salts of these amines. The observation of the optical data of pure crystalline substances is a good micro-identification method, especially when combined with micro melting point determina- tions. The purpose of this paper is to report some results obtained by the authors in chromatographic experiments with some sympathomimetic amines. The technique elaborated is believed to be useful in pharma- ceutical analysis, since identification of a substance by paper partition chromatography does not require its isolation in the pure crystalline state. The micro-identification of amphetamine and desoxy-ephedrine should be of particular interest, because these substances are sometimes wrongly used to produce a stimulating effect. The technique of paper partition chromatography may probably be used also in biochemical analysis for the detection of small quantities of sympathomimetic amines. Richter2 has shown that amphetamine and TI - The Separation and Identification of Some Sympathomimetic Amines by Paper Partition Chromatography JF - Journal of Pharmacy and Pharmacology DO - 10.1111/j.2042-7158.1952.tb13193.x DA - 1952-09-01 UR - https://www.deepdyve.com/lp/oxford-university-press/the-separation-and-identification-of-some-sympathomimetic-amines-by-2MwJgXR04c SP - 631 EP - 635 VL - 4 IS - 1 DP - DeepDyve ER -