TY - JOUR AU1 - Niwa, Motohiro AU2 - Kawakami, Hiroyoshi AU3 - Nagaoka, Shoji AU4 - Kanamori, Toshiyuki AU5 - Morisaku, Kazuko AU6 - Shinbo, Toshio AU7 - Matsuda, Toshiaki AU8 - Sakai, Kazunari AU9 - Kubota, Sunao AB - Abstract: We have developed a membrane oxygenator using a novel asymmetric polyimide hollow fiber. The hollow fibers are prepared using a dry/wet phase‐inversion process. The gas transfer rates of O2 and CO2 through the hollow fibers are investigated in gas–gas and gas–liquid systems. The polyimide hollow fiber has an asymmetric structure characterized by the presence of macrovoids, and the outer diameter of the hollow fiber is 330 µm. It is found that the polyimide hollow‐fiber oxygenator can enhance the gas transfer rates of O2 and CO2, and that the hollow fiber provides excellent blood compatibility in vitro and in vivo. TI - Development of a Novel Polyimide Hollow‐fiber Oxygenator JF - Artificial Organs DO - 10.1111/j.1525-1594.2004.07257.x DA - 2004-05-01 UR - https://www.deepdyve.com/lp/wiley/development-of-a-novel-polyimide-hollow-fiber-oxygenator-21uavi5oq0 SP - 487 VL - 28 IS - 5 DP - DeepDyve ER -