TY - JOUR AU - Tan, Chuanchuan AB - CORRESPONDENCE 1 parietal cell degeneration, or glandular endoscopic “field” evaluations may offer Letter to the shortening? According to Japanese di- a more accurate approach. We hope this agnostic criteria, such findings are con- perspective will inspire further discussion sidered early histological changes of AIG and investigation by the authors and the Editor (2). If present, they may suggest that the broader international community. autoimmune process had already com- We sincerely thank the authors for Xueli Shangguan, MD and menced, providing a plausible explanation their important contributions to the study Chuanchuan Tan, MD for anti-parietal cell antibody positivity. of AIG and look forward to future research We believe that clarifying these details that will deepen our understanding of its Am J Gastroenterol 2025;00:1. https://doi.org/ would enhance our understanding of how progression. 10.14309/ajg.0000000000003632 potential AIG progresses to its overt form. Second, we would like to reflect on the CONFLICTS OF INTEREST staging methodology used for AIG. Although Guarantor of the article: Chanchuan the authors performed standardized biopsies We read with great interest the recent ar- Tan, MD. from the antrum, corpus, and incisura ticle by Miceli et al on the natural history Specific author contributions: X.S.: Wrote angularis according to the TI - Letter to the Editor JF - American Journal of Gastroenterology DO - 10.14309/ajg.0000000000003632 DA - 2025-08-04 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/letter-to-the-editor-1vVwCpnZev VL - Publish Ahead of Print IS - DP - DeepDyve ER -