TY - JOUR AU1 - Marston, Judith AU2 - Fahlberg, W. J. AB - COAGULASE PRODUCTION BY STAPHYLOCOCCUS AUREUS II. GROWTH AND COAGULASE PRODUCTION IN COMPLEX AND CHEMICALLY DEFINED MEDIUMS-COMPARISON OF CHEMICALLY DEFINED MEDIUMS JUDITH MARSTON* AND W. J. FAHLBERG From the Department of Microbiology, Baylor University College of Medicine, Houston, Texas While the exact nature of coagulase 1937; Ramsey and Padron, 1954; and its mode of action remain enigmat­ Boniece, 1956), titers of coagulase are ic, experimental studies over the past low in similar mediums. Jacherts (1957) twenty years have contributed some­ reported coagulase production 111 a what to our knowledge of this substance chemically defined medium but no produced by the staphylococci. quantitative measurement of the ac­ The particulate nature of coagulase tivity was given. Szeto and Halick has been reported (Smith and Hale, (1958) modified the medium of Glad­ 1944) and it is regarded as a protein stone (1937) and obtained titers of 1: 8. with enzymatic activity (Duthie and In our investigations using a di­ Lorenz, 1952; Miale, 1949). Tager alysate of brain heart infusion (BHI) (1956) has also reported studies which as a reference medium, two markedly have established coagulase as a protein. different chemically defined mediums The ability of coagulase to bring were compared in an attempt TI - JF - The Journal of Infectious Diseases DO - 10.1093/infdis/106.2.116 DA - 1960-03-01 UR - https://www.deepdyve.com/lp/oxford-university-press/1rt7eV0Gpr SP - 116 EP - 122 VL - 106 IS - 2 DP - DeepDyve ER -