TY - JOUR
AU1 - Mastropasqua, Leonardo
AU2 - Toto, Lisa
AU3 - D’Ugo, Erminia
AU4 - Lanzini, Manuela
AU5 - Mattei, Peter A.
AU6 - Falconio, Gennaro
AU7 - Doronzo, Emanuele
AU8 - Diomede, Francesca
AU9 - Trubiani, Oriana
AB - PurposeTo compare the corneal tissue trauma after the use of an automated preloaded injector and a manual injector and assess scanning electron microscope (SEM) and atomic force microscope (AFM) features of both injector cartridges.SettingOphthalmology Clinic and Laboratory of Stem Cells and Regenerative Medicine University “G. d'Annunzio” of Chieti-Pescara, Chieti, Italy;DesignProspective randomized clinical studyMethodsForty eyes of 40 patients for phacoemulsification were divided into two groups: implantation of intraocular lens was performed with AutonoMe automated delivery system (AutonoMe group: 20 eyes) and Monarch III injector system (Monarch group: 20 eyes). In vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) were performed before surgery, at 1 h, 1 day and 1 month post-operatively. In addition, SEM and AFM were performed on cartridges of both injector systems after injection of the IOL.ResultsA greater increase in central corneal thickness and corneal thickness at the incision site were observed in Monarch group versus AutonoMe group 1 h and 1 day post-operatively (p < 0.05). Endothelial cell count loss was significantly higher in Monarch group compared with AutonoMe group (p < 0.05) at 1 and 24 h. AS-OCT showed less endothelial misalignment at 30 days (p < 0.05), and IVCM showed less tunnel inflammation at all time points (p < 0.05) in AutonoMe group compared with Monarch group; roughness analysis at AFM of the AutonoMe cartridge was significantly lower compared to Monarch D cartridge (p < 0.05).ConclusionsThe AutonoMe injector provided less corneal tissue trauma compared with Monarch III injector. The AutonoMe cartridge showed lower roughness at AFM compared to the Monarch D cartridge.
TI - In vivo and in vitro results of an automated preloaded delivery system for IOL implantation in cataract surgery
JF - International Ophthalmology
DO - 10.1007/s10792-019-01154-0
DA - 2020-01-26
UR - https://www.deepdyve.com/lp/springer-journals/in-vivo-and-in-vitro-results-of-an-automated-preloaded-delivery-system-1pbBlnEwso
SP - 125
EP - 134
VL - 40
IS - 1
DP - DeepDyve
ER -