TY - JOUR
AU - Inayama, Yoshiaki
AB - CASE REPORTS Urinary Cytologic Features of Primary Large Cell Neuroendocrine Carcinoma of the Urinary Bladder A Case Report Hisashi Oshiro, M.D., Kiyoshi Gomi, M.D., Kiyotaka Nagahama, M.D., Yoji Nagashima, M.D., Michiyo Kanazawa, M.T., Junji Kato, C.T., Takashi Hatano, M.D., and Yoshiaki Inayama, M.D., F.I.A.C. Background lymphadenectomy were performed. Based on the review of Little is known about urine cytology of large cell neuroen- urine cytology for this tumor, neoplastic cells possessed rosette docrine carcinoma (LCNEC) of the bladder. We report a and nuclear molding arrangements with finely or coarsely case of primary LCNEC of the bladder, focusing on urinary granular, hyperchromatic nuclei. The average nuclear size cytology. of the neoplastic cells was 10.3 μm, whereas the average cell size was 14.9 μm. These cells were immunocytochemically Case positive for synaptophysin, A 76-year-old woman who consistent with LCNEC. The had a history of transurethral Urine cytology in combination with postoperative course for this resection for urothelial carci- patient was uneventful, and morphometric and noma of the bladder visited LCNEC had not recurred in immunocytochemical analyses may our hospital because of inter- the 48 months since cystecto- mittent gross hematuria. Uri- my. contribute to early detection of nary cytology on this 
TI - Urinary Cytologic Features of Primary Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
JO - Acta Cytologica
DO - 10.1159/000325039
DA - 2011-01-01
UR - https://www.deepdyve.com/lp/karger/urinary-cytologic-features-of-primary-large-cell-neuroendocrine-1noEjSHqBf
SP - 303
EP - 310
VL - 54
IS - 3
DP - DeepDyve
ER -