TY - JOUR
AU1 - Daneshmend, T., K.
AB - Abstract The serum concentrations of miconazole were measured in 11 healthy adult females for 72 hours following a single 1200 mg vaginal pessary. The mean peak serum miconazok concentration was 10.4 ug/1 and the mean elimination half life was 56.8 h. The mean area under the serum concentration time curve was 967 μg/I.h. The calculated mean systemic bioavailability of the vaginal pessary was 1.4%. There was large intersubject variation in serum miconazole pharmacokinetics. This formulation may provide effective single dose treatment for vaginal candidosis. This content is only available as a PDF. © 1986, by The British Society for Antimicrobial Chemotherapy
TI - Systemic absorption of miconazole from the vagina
JF - Journal of Antimicrobial Chemotherapy
DO - 10.1093/jac/18.4.507
DA - 1986-10-01
UR - https://www.deepdyve.com/lp/oxford-university-press/systemic-absorption-of-miconazole-from-the-vagina-1j2d9ZgQn5
SP - 507
EP - 511
VL - 18
IS - 4
DP - DeepDyve
ER -