TY - JOUR AU1 - Hiersch, Liran AU2 - Shinar, Shiri AU3 - Melamed, Nir AU4 - Aviram, Amir AU5 - Hadar, Eran AU6 - Yogev, Yariv AU7 - Ashwal, Eran AB - Objective Increased birthweight is a risk factor for early neonatal complications, as well as cardiovascular and metabolic disease later in adulthood. We aimed to assess birthweight trends and the rate of large for gestational age newborns in women in their third delivery according to birthweight in the first and second deliveries. Study design A retrospective cohort study of all women who delivered their first three consecutive deliveries in a single medical center (1994–2013). Only non-diabetic women with term (≥ 37 weeks) singleton deliveries in all three deliveries were included. BW centile (according to local gender- and gestational age-specific birth curves) trends between deliveries was assessed. In addition, the risk for large for gestational age (≥ 90th centile) infants in the third delivery was assessed according to the presence or absence of large for gestational age in previous deliveries. Pregnancies complicated by multiple gestations, preeclampsia, chronic or gestational hypertension or fetal anomalies were excluded. Results Of the 121,728 deliveries during the study period, 3521 women (10,563 deliveries [8.6%]) met inclusion criteria. Mean birthweight centile in the first, second and third deliveries were 47.2 ± 26.3, 58.3 ± 25.8 and 61.5 ± 24.7, respectively (p < 0.001). While 45.9% women had their TI - Birthweight and large for gestational age trends in non-diabetic women with three consecutive term deliveries JF - Archives of Gynecology and Obstetrics DO - 10.1007/s00404-018-4872-8 DA - 2018-08-21 UR - https://www.deepdyve.com/lp/springer-journals/birthweight-and-large-for-gestational-age-trends-in-non-diabetic-women-1dVdB5NsM9 SP - 725 EP - 730 VL - 298 IS - 4 DP - DeepDyve ER -