TY - JOUR
AU - JENSEN,, H.
AB - Abstract THE interpretations of recent investigations of this laboratory on thyroid function under certain conditions of experimental stress (1–5) have been beset by the question of peripheral utilization and of excretion of released thyroid hormone.a1 In determining thyroid functional activity by the use of radioiodine (I131), the following considerations should be taken into account: 1. A. The amount of I131 in the gland after I131 administration is the resultant of the rate of uptake and of the degree of conversion and release from the gland. 2. B. The organic I131 in the blood is the resultant of the rate of release of hormone from the gland and the rate of utilization and excretion. In order to circumvent the in vivo influence of possible peripheral utilization and excretion of the thyroid hormone with regard to the physiologic state of the thyroid, in vitro studies were undertaken on the effect of thyroxin, thiocyanate or thyrotropic hormone (TSH) on the functional activity of the intact isolated gland. This content is only available as a PDF. Author notes * Presented at the Annual Meeting of the American Goiter Association, Boston, Mass. April 29–May 1, 1954. This article will be included in the bound volume of the 1954 “Transactions of the American Goiter Association” published by Charles C Thomas, Publisher, which will be available for purchase early in 1955. † Present address: 6303 N. Rockwell St., Chicago 45, Illinois. Copyright © 1954 by The Endocrine Society
TI - IN VITRO STUDIES OF THE INTACT THYROID GLAND
JF - Journal of Clinical Endocrinology and Metabolism
DO - 10.1210/jcem-14-10-1219
DA - 1954-10-01
UR - https://www.deepdyve.com/lp/oxford-university-press/in-vitro-studies-of-the-intact-thyroid-gland-189P3RZOFv
SP - 1219
EP - 1229
VL - 14
IS - 10
DP - DeepDyve
ER -