TY - JOUR
AU1 - Peng, Tingfa
AU2 - Deng, Lijuan
AU3 - Wang, Yuexing
AU4 - Wang, Ruilan
AU5 - Zeng, Fanqing
AU6 - Xie, Min
AU7 - Gou, Xiaopan
AU8 - Guo, Yulan
AU9 - Wu, Dongmei
AU1 - Peng, Fengxiang
AU1 - Gao, Rongmei
AU1 - Ye, Xiaojuan
AB - ObjectiveGastric mucosa-associated lymphoid tissue lymphoma is a rare disease, which is associated with a low endoscopic diagnostic accuracy even on tissue biopsy. We aimed to establish a diagnostic process system (M-system) using detailed magnifying endoscopy images to improve the diagnostic efficiency of this disease.MethodsFirst, 34 cases from 16 patients with the diagnosis of mucosa-associated lymphoid tissue lymphoma were collected as the study group. The control group included randomly selected patients who were diagnosed with early differentiated carcinoma, undifferentiated carcinoma or inflammation. Then, the endoscopic images of these patients were analyzed by senior physicians. Finally, the M-system was established based on the data extracted from the images reviewed, and its diagnostic efficiency for mucosa-associated lymphoid tissue lymphoma was validated by the junior physicians.ResultsA series of elements with high sensitivity and specificity for the diagnosis of mucosa-associated lymphoid tissue lymphoma on endoscopic images were extracted for the establishment of the M-system. Using the M-system, the diagnostic accuracy, sensitivity, specificity and correct indices of mucosa-associated lymphoid tissue lymphoma rose from 65.4 to 79.4%, 41.2 to 76.5%, 73.5 to 80.4% and 0.147 to 0.569%, respectively, all of which were statistically significant.ConclusionsThe M-system can improve the diagnostic accuracy of mucosa-associated lymphoid tissue lymphoma of the superficial-spreading type on detailed magnifying endoscopy. This would help in the early diagnosis of the disease and treatment, which would translate into improved clinical outcomes.
TI - Establishing an endoscopic diagnostic process system (M-system) for gastric MALT lymphoma of superficial-spreading type
JF - Japanese Journal of Clinical Oncology
DO - 10.1093/jjco/hyaa242
DA - 2021-01-13
UR - https://www.deepdyve.com/lp/oxford-university-press/establishing-an-endoscopic-diagnostic-process-system-m-system-for-16AGHa0NG7
SP - 560
EP - 568
VL - 51
IS - 4
DP - DeepDyve
ER -