TY - JOUR AU - Schröder, Cornelis H. AB - Continuous ambulatory peritoneal dialysis (CAPD) and nightly intermittent peritoneal dialysis (NIPD) in young children with end-stage renal failure are often associated with feeding disturbances such as ano- rexia, nausea, and vomiting. These feeding disturbances are likely caused by chronic renal failure and its treatment. Because little is known about the mechanism underlying feeding disturbances in young children treated with PD, we examined the existence of a pathological gastroesophageal reflux (GER) and quantified intesti- nal passage by measuring the mouth-to-cecum transit time (MCTT) in young children treated with PD. Patients and Methods After obtaining written informed consent from each patient’s relatives, the MCTT and the presence of pathological GER were evaluated in children treated with PD. All children had end-stage renal disease and were without prokinetics or other drugs with known influence on gastrointestinal function. This study was approved by the local ethics committee. In 8 children treated with CAPD (four daily exchanges of 40 mL/kg; mean age 5.0 years, range 0.2 – 9.6 years) the MCTT was investigated by a lactulose hydrogen breath test, using a Lactoscreen (Hoekloos, Schiedam, The Netherlands) as described by Van der Klei et al . (1). None of the patients had feeding disturbances. Basal TI - Gastrointestinal Motor Function in Children Treated with Peritoneal Dialysis JF - Peritoneal Dialysis International DO - 10.1177/089686080102100116 DA - 2001-01-01 UR - https://www.deepdyve.com/lp/sage/gastrointestinal-motor-function-in-children-treated-with-peritoneal-0sSH9jOLSe SP - 1 EP - 3 VL - 21 IS - 1 DP - DeepDyve ER -