TY - JOUR
AB - CLINICA L CHEMISTRY The separation of serum pigments (jiving the direct and indirect van den Bergh reaction. P. G. COL E and G. H . LATHE . J. Clin. Path . (British), 6: 99-104, 1953. Th e authors discuss present concepts of the bile pigments and rationale of their differ­ entiatio n in variou s kinds of jaundice . I n the course of investigatin g bile pigments in kern- icteru s by use of chromatography methods, they have found it possible to separate the direc t and indirect-reacting pigments. Using the reverse phase kieselguhr columns, the direct-reactin g pigments, being more soluble in th e moving aqueous phase, come off first. Thi s is followed by the slower moving pigment. Th e authors discuss th e previou s views on th e mechanis m of th e indirec t van de n Bergh reactio n in relationship to protein binding. They conclude that the pigments, when pre­ pare d by th e metho d used, contain no protei n and the y believe tha t reaction docs not de ­ pend upon the splitting by alcohol of the linkage with protein but on the existence of 2 type 
TI - Selected Abstracts
JF - American Journal of Clinical Pathology
DO - 10.1093/ajcp/24.1.82
DA - 1954-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/selected-abstracts-0puV2faOwi
SP - 82
EP - 98
VL - 24
IS - 1
DP - DeepDyve
ER -