TY - JOUR AB - References 1 Sakuramoto S , Sasako M, Yamaguchi T, Kinoshita T, Fujii M, Nashimoto A et al. Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine . N Engl J Med 2007 ; 357 : 1810 – 1820 . Google Scholar Crossref Search ADS PubMed WorldCat The addition of a year of oral chemotherapy to extended resection improved 3- year survival from 70·1 to 80·1 per cent (P = 0·003) in this study that included 529 patients. 2 Peeters KCMJ , Marijnen CAM, Nagtegaal ID, Kranenbarg EK, Putter H, Wiggers T et al. The TME trial after a median follow-up of 6 years: local control but no survival benefit in irradiated patients with resectable rectal carcinoma . Ann Surg 2007 ; 246 : 693 – 701 . Google Scholar Crossref Search ADS PubMed WorldCat The addition of preoperative radiotherapy reduced local recurrence from 10·9 to 5·6 per cent (P < 0·001), but had no effect on overall survival (64·2 versus 63·5 per cent, respectively), in this study that included 1861 procedures. 3 Chung CC , Ng DCK, Tsang WWC, Tang WL, Yau KKK, Cheung HYS et al. Hand-assisted laparoscopic versus open right colectomy: a randomized controlled trial . Ann Surg 2007 ; 246 : 728 – 733 . Google Scholar Crossref Search ADS PubMed WorldCat The laparoscopic procedure took longer, but was associated with less blood loss, less postoperative pain and shorter hospital stay (7 versus 9 days, P = 0·004). After a median 30 months of follow-up there was no difference in survival or recurrence rates in the 81 patients studied. 4 Braga M , Frasson M, Vignali A, Zuliani W, Di Carlo V. Open right colectomy is still effective compared to laparoscopy: results of a randomized trial . Ann Surg 2007 ; 246 : 1010 – 1015 . Google Scholar Crossref Search ADS PubMed WorldCat In this study that included 226 procedures, 3/113 laparoscopic operations required conversion to open. The laparoscopic procedure took longer but was associated with 1 day less in hospital (P = 0·002). Perioperative complications and quality of life were similar. 5 Smeenk HG , van Eijck CHJ, Hop WC, Erdmann J, Tran KCK, Debois M et al. Long term survival and metastatic pattern of pancreatic and periampullary cancer after adjuvant chemoradiation or observation: long term results of EORTC Trial 40 891 . Ann Surg 2007 ; 246 : 734 – 740 . Google Scholar Crossref Search ADS PubMed WorldCat After a median of 11·7 years, only 45 of the original 218 patients remained alive. The addition of chemoradiotherapy had no effect on survival: mortality ratio 0·91, 95 per cent confidence interval 0·68 to 1·23, P = 0·54. 6 Westerdahl J , Bergenfelz A. Unilateral versus bilateral neck exploration for primary hyperparathyroidism: 5- year follow-up of a randomized controlled trial . Ann Surg 2007 ; 246 : 976 – 981 . Google Scholar Crossref Search ADS PubMed WorldCat Seventy-one of the original 91 patients were available for study at 5 years. Six had persistent (n = 3) or recurrent (n = 3) hyperparathyroidism. Of the four that originally had unilateral exploration, three had been explored bilaterally. Thus the initial unilateral exploration strategy was equally effective. 7 Omloo JMT , Lagarde S, Hulscher JBF, Reitsma JB, Fockens P, van Dekken H et al. Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the mid/distal esophagus: 5- year survival of a randomized clinical trial . Ann Surg 2007 ; 246 : 992 – 1001 . Google Scholar Crossref Search ADS PubMed WorldCat There was an emerging trend towards improved survival after extended surgery after 5 years (37 versus 51 per cent) that did not reach statistical significance. The benefit was most evident in patients with a limited number of involved lymph nodes in the resection specimen. 8 Bright T , Watson DI, Tam W, Game PA, Astill D, Ackroyd R et al. Randomized trial of argon plasma coagulation versus endoscopic surveillance for Barrett esophagus after antireflux surgery: late results . Ann Surg 2007 ; 246 : 1016 – 1020 . Google Scholar Crossref Search ADS PubMed WorldCat After 5 years, at least 95 per cent regression of Barrett's was seen in 14/20 ablated and 5/20 control subjects. Two patients who had ablation developed a stricture and two under surveillance alone developed high-grade dysplasia on biopsy. 9 Prinssen M , Buskens E, de Jonge SE, Buth J, Mackaay AJ, Sambeek MR et al. on behalf of the DREAM Trial participants . Cost-effectiveness of conventional and endovascular repair of abdominal aortic aneurysms: results of a randomized trial . J Vasc Surg 2007 ; 46 : 883 – 890 . Google Scholar Crossref Search ADS PubMed WorldCat Costs and quality of life were recorded for 1 year after intervention in this trial that included 351 procedures. There was no significant difference in the quality of life scores, but endovascular repair was more expensive. 10 Takagi H , Sekino S, Kato T, Matsuno Y, Umemoto T. Intraoperative autotransfusion in abdominal aortic aneurysm surgery: meta-analysis of the randomized controlled trials . Arch Surg 2007 ; 142 : 1098 – 1101 . Google Scholar Crossref Search ADS PubMed WorldCat Four trials including 292 procedures were analysed. Intraoperative autotransfusion reduced the rate of allogeneic blood transfusion by 37 per cent: risk ratio 0·63, 95 per cent confidence interval 0·41 to 0·95, P = 0·03. 11 The trials listed here are added to the Scientific Surgery Archive which contains all randomized clinical trials in Surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. The Archive, which is fully searchable, can be found on the BJS website (www.bjs.co.uk) together with other useful features for surgeons such as Instructions to Authors, EarlyView of accepted articles and on-line Correspondence. Article PDF first page preview Close This content is only available as a PDF. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. TI - Scientific surgery JO - British Journal of Surgery DO - 10.1002/bjs.6205 DA - 2008-03-04 UR - https://www.deepdyve.com/lp/oxford-university-press/scientific-surgery-0lG1jOgIu3 SP - 536 EP - 536 VL - 95 IS - 4 DP - DeepDyve ER -