TY - JOUR AB - 21-22 March 1969 DEMONSTRATIONS Equipment for the collection and analysis of ultra-small specimens of the inner ear fluids of the rat By S. K. BOSHER, C. S. HALLPIKE, D. PIPER and R. L. WARREN. Ferens Institute of Otolaryngology and S. A. Courtauld Institute of Biochemistry, Middlesex Hospital Medical School, London, W. 1 The apparatus demonstrated was designed to improve the precision of the methods used for the collection, manipulation and analysis of very small uncontaminated specimens of the inner ear fluids of the rat and for the measurement of the endolymphatic potentials in the same animals. To eliminate risk of deterioration in the animal's condition all the microdissection, electrical measurements and fluid collections were completed in both ears within 1 hr, making operative speed vital. These manipulations were greatly facilitated by the firm fixation of the head provided by a specially designed claw clamp, giving a firm four-point grip upon the edges of the bony plate connecting the superior margins of the orbits. The clamp was securely mounted in an arrangement of gimbals with their axes traversing the cochlea. With this positioned at the point of focus of the microscope it was easy to impart to it the TI - Proceedings of the Physiological Society, 21–22 March 1969, University College London Meeting: Demonstrations JF - The Journal of Physiology DO - 10.1113/jphysiol.1969.sp008843 DA - 1969-12-01 UR - https://www.deepdyve.com/lp/wiley/proceedings-of-the-physiological-society-21-22-march-1969-university-0fZNAXtxHb SP - 49 EP - 82 VL - 202 IS - suppl DP - DeepDyve ER -