TY - JOUR
AU1 - Nifontov, V.
AU2 - Akishina, R.
AU3 - Grishakov, A.
AU4 - Yurkevich, A.
AB - METHODS OF SYNTHESIS AND TECHNOLOGY OF DRUG PRODUCTION V. I. Nifontov, R. I. Akishina, UDC 615.272:547.455. A. N. Grishakov, and A. M. Yurkevich 522].012(048.8) D-Ribose and some of its derivatives play an exceptionally important role in the metabolismof plant and animal cells -- the metabolism of nucleic acids, proteins, carbohy- drates, lipids, etc. The importance of carbohydrates, especially (I), is extremely high in the field of the directed synthesis of substances possessing biological activity, such as antiviral and antitumoral properties. Suchproperties have been detected in ribosylated analogues of free nitrogen bases -- purines and pyrimidines. Compound (I) has found wide use in industrial chemical synthesis of vitamin Ba (riboflavin) [8]. It must be mentioned that, as a rule, schemes for the synthesis of nucleosides include as a necessary stage the ribosylation of a nitrogen base with activated derivatives of (I) the preparation which requires the use of the chemically pure initial carbohydrate. This circumstance prevents the use in the synthesis of nucleotides of (I) isolated from technical solutions in the form of a noncrystallizing syrup contaminated with sugars having an anomer- ic structure and also with the corresponding polyols. The increasing interest at the present time in the chemistry 
TI - Methods of preparing and isolating D-ribose [review]
JF - Pharmaceutical Chemistry Journal
DO - 10.1007/BF00757492
DA - 2004-11-22
UR - https://www.deepdyve.com/lp/springer-journals/methods-of-preparing-and-isolating-d-ribose-review-0W0prSPd5o
SP - 358
EP - 369
VL - 21
IS - 5
DP - DeepDyve
ER -