TY - JOUR
AU - Picard, Capucine
AB - 
CD8A encodes the CD8α chain of the dimeric CD8 protein, a critical coreceptor of cytotoxic T cells. We report here the comprehensive immunological evaluation of a child with a CD8A missense mutation, providing evidence that CD8 deficiency increases susceptibility to recurrent respiratory infections without interfering with the TCR-mediated proliferation of T cells. These observations expand the known phenotypes associated with CD8 deficiency.
TI - Recurrent Respiratory Infections Revealing CD8α Deficiency
JF - Journal of Clinical Immunology
DO - 10.1007/s10875-015-0213-x
DA - 2015-11-12
UR - https://www.deepdyve.com/lp/springer-journals/recurrent-respiratory-infections-revealing-cd8-deficiency-0V19OWvg49
SP - 692
EP - 695
VL - 35
IS - 8
DP - DeepDyve
ER -