TY - JOUR AU - Halle, Martin AB - Key PointsQuestionIs there a difference in change in peak oxygen consumption (V̇o2) among patients with heart failure with preserved ejection fraction (HFpEF) treated with differing modes of exercise? FindingsThis randomized clinical trial included 180 patients with HFpEF assigned to high-intensity interval training, moderate continuous training, or a control of guideline-based physical activity advice. At 3 months, the changes in peak V̇o2 were 1.1, 1.6, and −0.6 mL/kg/min, respectively. There was no statistically significant difference between high-intensity interval and moderate continuous training, and neither group met the a priori–defined minimal clinically important difference of 2.5 mL/kg/min compared with the guideline control. MeaningThese findings do not support either high-intensity interval training or moderate continuous training compared with guideline-based physical activity for patients with HFpEF. TI - Effect of High-Intensity Interval Training, Moderate Continuous Training, or Guideline-Based Physical Activity Advice on Peak Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction JF - JAMA DO - 10.1001/jama.2020.26812 DA - 2021-02-09 UR - https://www.deepdyve.com/lp/american-medical-association/effect-of-high-intensity-interval-training-moderate-continuous-0OaYnF0anl SP - 542 EP - 551 VL - 325 IS - 6 DP - DeepDyve ER -