TY - JOUR AU - Zanetti, Krista AB - Metabolomics (2014) 10:176–178 DOI 10.1007/s11306-014-0636-z OPINION Navigating the road ahead: addressing challenges for use of metabolomics in epidemiology studies • • • • Majda Haznadar Padma Maruvada Eliza Mette John Milner • • • Steven C. Moore Holly L. Nicastro Joshua N. Sampson • • L. Joseph Su Mukesh Verma Krista A. Zanetti Springer Science+Business Media New York 2014 Metabolomics platforms allow for the measurement of Common Fund’s Metabolomics Program (https://common hundreds to thousands of unique small chemical entities, as fund.nih.gov/metabolomics/index), it is time to consider well as offer extensive coverage of metabolic markers those challenges most pertinent to epidemiologic studies. related to obesity, diet, smoking, and other exposures of high interest to health scientists. Nevertheless, its potential use as a tool in population-based study design has not been 1 Study-level challenges fully explored. As the field of metabolomics continues to mature, and in part, accelerate through the National Insti- To design and conduct high quality studies, at minimum tutes of Health (NIH) investment of $65 million in the the investigator must identify the general biological path- ways of interest, the number of study participants and identify metabolomic endpoints a priori. Metabolomics provides a broad assessment of biology; therefore, TI - Navigating the road ahead: addressing challenges for use of metabolomics in epidemiology studies JF - Metabolomics DO - 10.1007/s11306-014-0636-z DA - 2014-02-12 UR - https://www.deepdyve.com/lp/springer-journals/navigating-the-road-ahead-addressing-challenges-for-use-of-0MsY18KIKW SP - 176 EP - 178 VL - 10 IS - 2 DP - DeepDyve ER -