TY - JOUR
AU - Ichimura, Hiroshi
AB - 1540 Correspondence JID 2001;183 (15 May) Reprints or correspondence: Dr. Jean-Michel Molina, Dept. of Infectious Dis- is not surprising, since, if 1 dose is missed, the next dose is eases, Saint-Louis Hospital, 1 avenue C. Vellefaux, 75010 Paris, France (molina likely to be taken 24 h later in a once-daily regimen. In the @chu-stlouis.fr). same study, however, the mean number of drug holidays (de- The Journal of Infectious Diseases 2001; 183:1539–40 fined as 13 days without medication) was similar with once- 2001 by the Infectious Diseases Society of America. All rights reserved. or twice-daily regimens. The real impact of drug holidays on 0022-1899/2001/18310-0017$02.00 treatment failure with once-daily regimens is difficult to assess; however, our results may be reassuring. After 48 weeks of treat- Prenatal Short-Course Zidovudine Reduces Mortality ment with a once-daily combination of emtricitabine, dida- in Children Born to Human Immunodeficiency nosine, and efavirenz, 38 (95%) of 40 patients maintained a Virus–Positive Mothers in Rural Kenya plasma HIV RNA level !400 copies/mL, and only 1 noncom- pliant patient experienced virologic failure [6]. To the Editor—Kuhn et al. [1] reported rapid progression to We agree with Parienti et al. [1] that further studies are needed AIDS and increased mortality 
TI - Prenatal Short-Course Zidovudine Reduces Mortality in Children Born to Human Immunodeficiency Virus–Positive Mothers in Rural Kenya
JO - Journal of Infectious Diseases
DO - 10.1086/320204
DA - 2001-05-15
UR - https://www.deepdyve.com/lp/oxford-university-press/prenatal-short-course-zidovudine-reduces-mortality-in-children-born-to-03pCvJgmWv
SP - 1540
EP - 1541
VL - 183
IS - 10
DP - DeepDyve
ER -