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ORIGINAL RESEARCH ADULT BRAIN Clinical and Neuroimaging Correlation in Patients with COVID-19 B.C. Yoon, K. Buch, M. Lang, B.P. Applewhite, M.D. Li, W.A. Mehan, Jr, T.M. Leslie-Mazwi, and S.P. Rincon ABSTRACT BACKGROUND AND PURPOSE: Coronavirus disease 2019 (COVID-19) is increasingly being recognized for its multiorgan involvement, including various neurological manifestations. We examined the frequency of acute intracranial abnormalities seen on CT and/or MR imaging in patients with COVID-19 and investigated possible associations between these findings and clinical parameters, includ- ing length of hospital stay, requirement for intubation, and development of acute kidney injury. MATERIALS AND METHODS: This was a retrospective study performed at a large academic hospital in the United States. A total of 641 patients presented to our institution between March 3, 2020, and May 6, 2020, for treatment of coronavirus disease 2019, of whom, 150 underwent CT and/or MR imaging of the brain. CT and/or MR imaging examinations were evaluated for the presence of hemorrhage, infarction, and leukoencephalopathy. The frequency of these findings was correlated with clinical variables, includ- ing body mass index, length of hospital stay, requirement for intubation, and development of acute kidney injury as documented in the electronic medical record. RESULTS: Of the 150
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Oct 1, 2020
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