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MRI Predictors of Recurrence and Outcome after Acute Transverse Myelitis of Unidentified Etiology

MRI Predictors of Recurrence and Outcome after Acute Transverse Myelitis of Unidentified Etiology ORIGINAL RESEARCH SPINE MRI Predictors of Recurrence and Outcome after Acute Transverse Myelitis of Unidentified Etiology X E. Bulut, X T. Shoemaker, X J. Karakaya, X D.M. Ray, X M.A. Mealy, X M. Levy, and X I. Izbudak ABSTRACT BACKGROUND AND PURPOSE: The early prediction of recurrence after an initial event of transverse myelitis helps to guide preventive treatment and optimize outcomes. Our aim was to identify MR imaging findings predictive of relapse and poor outcome in patients with acute transverse myelitis of unidentified etiology. MATERIALS AND METHODS: Spinal MRIs of 77 patients (mean age, 36.3  20 years) diagnosed with acute transverse myelitis were evaluatedretrospectively.Onlythepatientsforwhomanunderlyingcauseofmyelitiscouldnotbeidentifiedwithin3monthsofsymptom onset were included. Initial spinal MR images of patients were examined in terms of lesion extent, location and distribution, brain stem extension, cord expansion, T1 signal, contrast enhancement, and the presence of bright spotty lesions and the owl’s eyes sign. The relapse rates and Kurtzke Expanded Disability Status Scale scores at least 1 year (range, 1–14 years) after a myelitis attack were also recorded. Associations of MR imaging findings with clinical variables were studied with univariate associations and binary log-linear regression. Differences were considered significant for P values  .05. RESULTS: Twenty-seven patients http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

MRI Predictors of Recurrence and Outcome after Acute Transverse Myelitis of Unidentified Etiology

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References (18)

Publisher
American Journal of Neuroradiology
Copyright
© 2019 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A6121
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL RESEARCH SPINE MRI Predictors of Recurrence and Outcome after Acute Transverse Myelitis of Unidentified Etiology X E. Bulut, X T. Shoemaker, X J. Karakaya, X D.M. Ray, X M.A. Mealy, X M. Levy, and X I. Izbudak ABSTRACT BACKGROUND AND PURPOSE: The early prediction of recurrence after an initial event of transverse myelitis helps to guide preventive treatment and optimize outcomes. Our aim was to identify MR imaging findings predictive of relapse and poor outcome in patients with acute transverse myelitis of unidentified etiology. MATERIALS AND METHODS: Spinal MRIs of 77 patients (mean age, 36.3  20 years) diagnosed with acute transverse myelitis were evaluatedretrospectively.Onlythepatientsforwhomanunderlyingcauseofmyelitiscouldnotbeidentifiedwithin3monthsofsymptom onset were included. Initial spinal MR images of patients were examined in terms of lesion extent, location and distribution, brain stem extension, cord expansion, T1 signal, contrast enhancement, and the presence of bright spotty lesions and the owl’s eyes sign. The relapse rates and Kurtzke Expanded Disability Status Scale scores at least 1 year (range, 1–14 years) after a myelitis attack were also recorded. Associations of MR imaging findings with clinical variables were studied with univariate associations and binary log-linear regression. Differences were considered significant for P values  .05. RESULTS: Twenty-seven patients

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Aug 1, 2019

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