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MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical Dysplasia: A Quantitative Study

MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical... ORIGINAL RESEARCH PEDIATRICS MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical Dysplasia: A Quantitative Study X Z. Liu, X W. Hu, X Z. Sun, X X. Wang, X L. Liu, X X. Shao, X K. Zhang, X Y. Ma, and X J. Zhang ABSTRACT BACKGROUND AND PURPOSE: Type II focal cortical dysplasia is a common histopathological substrate in focal epilepsy. This study exploredthespatialdistributionofabnormalfindingsonMRimagingacrossthesulcuswithtypeIIfocalcorticaldysplasiausingquantitative MR imaging postprocessing techniques. MATERIALS AND METHODS: The morphometric analysis program and normalized FLAIR signal intensity analysis were applied to retro- spectively analyze the MR imaging data of 58 patients with histopathologically confirmed type II focal cortical dysplasia. We divided the dysplastic sulcus into the bottom and nonbottom parts. Then spatial distribution types 1, 2, and 3 were arbitrarily defined as the abnormal findings on MR imaging (z-value threshold) located in the bottom part, both the bottom and nonbottom parts, and the nonbottom part, respectively. For type 2, the mean z-values and standardized volumes of abnormal findings on MR imaging were compared between the bottom and nonbottom parts. RESULTS: Abnormal findings on MR imaging were detected by quantitative techniques in 42 of 58 enrolled patients. Among these 42 patients, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical Dysplasia: A Quantitative Study

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References (35)

Publisher
American Journal of Neuroradiology
Copyright
© 2019 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A5919
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL RESEARCH PEDIATRICS MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical Dysplasia: A Quantitative Study X Z. Liu, X W. Hu, X Z. Sun, X X. Wang, X L. Liu, X X. Shao, X K. Zhang, X Y. Ma, and X J. Zhang ABSTRACT BACKGROUND AND PURPOSE: Type II focal cortical dysplasia is a common histopathological substrate in focal epilepsy. This study exploredthespatialdistributionofabnormalfindingsonMRimagingacrossthesulcuswithtypeIIfocalcorticaldysplasiausingquantitative MR imaging postprocessing techniques. MATERIALS AND METHODS: The morphometric analysis program and normalized FLAIR signal intensity analysis were applied to retro- spectively analyze the MR imaging data of 58 patients with histopathologically confirmed type II focal cortical dysplasia. We divided the dysplastic sulcus into the bottom and nonbottom parts. Then spatial distribution types 1, 2, and 3 were arbitrarily defined as the abnormal findings on MR imaging (z-value threshold) located in the bottom part, both the bottom and nonbottom parts, and the nonbottom part, respectively. For type 2, the mean z-values and standardized volumes of abnormal findings on MR imaging were compared between the bottom and nonbottom parts. RESULTS: Abnormal findings on MR imaging were detected by quantitative techniques in 42 of 58 enrolled patients. Among these 42 patients,

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Jan 1, 2019

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