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Pre- and Postcontrast 3D Double Inversion Recovery Sequence in Multiple Sclerosis: A Simple and Effective MR Imaging Protocol

Pre- and Postcontrast 3D Double Inversion Recovery Sequence in Multiple Sclerosis: A Simple and... ORIGINAL RESEARCH ADULT BRAIN Pre- and Postcontrast 3D Double Inversion Recovery Sequence in Multiple Sclerosis: A Simple and Effective MR Imaging Protocol X P. Eichinger, X J.S. Kirschke, X M.-M. Hoshi, X C. Zimmer, X M. Mu¨hlau, and X I. Riederer ABSTRACT BACKGROUND AND PURPOSE: The double inversion recovery sequence is known to be very sensitive and specific for MS-related lesions. Our aim was to compare the sensitivity of pre- and postcontrast images of 3D double inversion recovery and conventional 3D T1-weighted images for the detection of contrast-enhancing MS-related lesions in the brain to analyze whether double inversion recovery could be as effective as T1WI. MATERIALSANDMETHODS: Apostcontrast3DdoubleinversionrecoverysequencewasacquiredinadditiontothestandardMRimaging protocol at 3T, including pre- and postcontrast 3D T1WI sequences as well as precontrast double inversion recovery of 45 consecutive patients with MS or clinically isolated syndrome between June and December 2013. Two neuroradiologists independently assessed precontrast,postcontrast,andsubtractionimagesofdoubleinversionrecoveryaswellasT1WItocountthenumberofcontrast-enhancing lesions. Afterward, a consensus reading was performed. Lin concordance was calculated between both radiologists, and differences in lesion detectability were assessed with the Student t test. Additionally, the contrast-to-noise ratio was calculated. RESULTS: Significantly more contrast-enhancing lesions could be detected with double inversion recovery compared with T1WI (16%, 214 versus 185, P  .007). The http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Pre- and Postcontrast 3D Double Inversion Recovery Sequence in Multiple Sclerosis: A Simple and Effective MR Imaging Protocol

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References (20)

Publisher
American Journal of Neuroradiology
Copyright
© 2017 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A5329
Publisher site
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Abstract

ORIGINAL RESEARCH ADULT BRAIN Pre- and Postcontrast 3D Double Inversion Recovery Sequence in Multiple Sclerosis: A Simple and Effective MR Imaging Protocol X P. Eichinger, X J.S. Kirschke, X M.-M. Hoshi, X C. Zimmer, X M. Mu¨hlau, and X I. Riederer ABSTRACT BACKGROUND AND PURPOSE: The double inversion recovery sequence is known to be very sensitive and specific for MS-related lesions. Our aim was to compare the sensitivity of pre- and postcontrast images of 3D double inversion recovery and conventional 3D T1-weighted images for the detection of contrast-enhancing MS-related lesions in the brain to analyze whether double inversion recovery could be as effective as T1WI. MATERIALSANDMETHODS: Apostcontrast3DdoubleinversionrecoverysequencewasacquiredinadditiontothestandardMRimaging protocol at 3T, including pre- and postcontrast 3D T1WI sequences as well as precontrast double inversion recovery of 45 consecutive patients with MS or clinically isolated syndrome between June and December 2013. Two neuroradiologists independently assessed precontrast,postcontrast,andsubtractionimagesofdoubleinversionrecoveryaswellasT1WItocountthenumberofcontrast-enhancing lesions. Afterward, a consensus reading was performed. Lin concordance was calculated between both radiologists, and differences in lesion detectability were assessed with the Student t test. Additionally, the contrast-to-noise ratio was calculated. RESULTS: Significantly more contrast-enhancing lesions could be detected with double inversion recovery compared with T1WI (16%, 214 versus 185, P  .007). The

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Oct 1, 2017

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