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Synthetic MRI in the Detection of Multiple Sclerosis Plaques

Synthetic MRI in the Detection of Multiple Sclerosis Plaques ORIGINALRESEARCH ADULT BRAIN X A. Hagiwara, X M. Hori, X K. Yokoyama, X M.Y. Takemura, X C. Andica, X T. Tabata, X K. Kamagata, X M. Suzuki, X K.K. Kumamaru, X M. Nakazawa, X N. Takano, X H. Kawasaki, X N. Hamasaki, X A. Kunimatsu, and X S. Aoki ABSTRACT BACKGROUND AND PURPOSE: Synthetic MR imaging enables the creation of various contrast-weighted images including double inversion recovery and phase-sensitive inversion recovery from a single MR imaging quantification scan. Here, we assessed whether synthetic MR imaging is suitable for detecting MS plaques. MATERIALS AND METHODS: Quantitative and conventional MR imaging data on 12 patients with MS were retrospectively analyzed. Synthetic T2-weighted, FLAIR, double inversion recovery, and phase-sensitive inversion recovery images were produced after quantifica- tion of T1 and T2 values and proton density. Double inversion recovery images were optimized for each patient by adjusting the TI. The number of visible plaques was determined by a radiologist for a set of these 4 types of synthetic MR images and a set of conventional T1-weighted inversion recovery, T2-weighted, and FLAIR images. Conventional 3D double inversion recovery and other available images were used as the criterion standard. The total acquisition time of synthetic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

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References (28)

Publisher
American Journal of Neuroradiology
Copyright
© 2017 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A5012
pmid
27932506
Publisher site
See Article on Publisher Site

Abstract

ORIGINALRESEARCH ADULT BRAIN X A. Hagiwara, X M. Hori, X K. Yokoyama, X M.Y. Takemura, X C. Andica, X T. Tabata, X K. Kamagata, X M. Suzuki, X K.K. Kumamaru, X M. Nakazawa, X N. Takano, X H. Kawasaki, X N. Hamasaki, X A. Kunimatsu, and X S. Aoki ABSTRACT BACKGROUND AND PURPOSE: Synthetic MR imaging enables the creation of various contrast-weighted images including double inversion recovery and phase-sensitive inversion recovery from a single MR imaging quantification scan. Here, we assessed whether synthetic MR imaging is suitable for detecting MS plaques. MATERIALS AND METHODS: Quantitative and conventional MR imaging data on 12 patients with MS were retrospectively analyzed. Synthetic T2-weighted, FLAIR, double inversion recovery, and phase-sensitive inversion recovery images were produced after quantifica- tion of T1 and T2 values and proton density. Double inversion recovery images were optimized for each patient by adjusting the TI. The number of visible plaques was determined by a radiologist for a set of these 4 types of synthetic MR images and a set of conventional T1-weighted inversion recovery, T2-weighted, and FLAIR images. Conventional 3D double inversion recovery and other available images were used as the criterion standard. The total acquisition time of synthetic

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Feb 1, 2017

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