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ORIGINALRESEARCH ADULT BRAIN X A. Hagiwara, X M. Hori, X K. Yokoyama, X M.Y. Takemura, X C. Andica, X T. Tabata, X K. Kamagata, X M. Suzuki, X K.K. Kumamaru, X M. Nakazawa, X N. Takano, X H. Kawasaki, X N. Hamasaki, X A. Kunimatsu, and X S. Aoki ABSTRACT BACKGROUND AND PURPOSE: Synthetic MR imaging enables the creation of various contrast-weighted images including double inversion recovery and phase-sensitive inversion recovery from a single MR imaging quantification scan. Here, we assessed whether synthetic MR imaging is suitable for detecting MS plaques. MATERIALS AND METHODS: Quantitative and conventional MR imaging data on 12 patients with MS were retrospectively analyzed. Synthetic T2-weighted, FLAIR, double inversion recovery, and phase-sensitive inversion recovery images were produced after quantifica- tion of T1 and T2 values and proton density. Double inversion recovery images were optimized for each patient by adjusting the TI. The number of visible plaques was determined by a radiologist for a set of these 4 types of synthetic MR images and a set of conventional T1-weighted inversion recovery, T2-weighted, and FLAIR images. Conventional 3D double inversion recovery and other available images were used as the criterion standard. The total acquisition time of synthetic
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Feb 1, 2017
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