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SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T ( P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T. ABBREVIATIONS: AUC area under the curve CNR contrast-to-noise ratio DCE dynamic contrast-enhanced K trans volume transfer constant v e extravascular extracellular volume fraction v p blood plasma fraction
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Jan 1, 2017
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