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Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions

Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T ( P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T. ABBREVIATIONS: AUC area under the curve CNR contrast-to-noise ratio DCE dynamic contrast-enhanced K trans volume transfer constant v e extravascular extracellular volume fraction v p blood plasma fraction http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Dynamic Contrast-Enhanced MR Perfusion of Intradural Spinal Lesions

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References (9)

Publisher
American Journal of Neuroradiology
Copyright
Copyright © 2017 by the American Society of Neuroradiology.
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A4995
pmid
27856434
Publisher site
See Article on Publisher Site

Abstract

SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T ( P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T. ABBREVIATIONS: AUC area under the curve CNR contrast-to-noise ratio DCE dynamic contrast-enhanced K trans volume transfer constant v e extravascular extracellular volume fraction v p blood plasma fraction

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Jan 1, 2017

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