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Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores: Recanalization Rates, Periprocedural Complications, and Clinical Outcome

Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores:... ORIGINAL RESEARCH INTERVENTIONAL Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores: Recanalization Rates, Periprocedural Complications, and Clinical Outcome X J. Pfaff, X C. Herweh, X M. Pham, X S. Scho¨nenberger, X S. Nagel, X P.A. Ringleb, X M. Bendszus, and X M. Mo¨hlenbruch ABSTRACT BACKGROUND AND PURPOSE: Mechanical thrombectomy, in addition to intravenous thrombolysis, has become standard in acute ischemic stroke treatment in patients with large-vessel occlusion in the anterior circulation. However, previous randomized controlled stroke trials were not focused on patients with mild-to-moderate symptoms. Thus, there are limited data for patient selection, prediction of clinical outcome, and occurrence of complications in this patient population. The purpose of this analysis was to assess clinical and interventional data in patients treated with mechanical thrombectomy in case of ischemic stroke with mild-to-moderate symptoms. MATERIALSANDMETHODS: Weperformedaretrospectiveanalysisofaprospectivelycollectedstrokedatabase.Inclusioncriteriawere anterior circulation ischemic stroke treated with mechanical thrombectomy at our institution between September 2010 and October 2015 with an NIHSS score of 8. RESULTS: Of 484 patients, we identified 33 (6.8%) with the following characteristics: median NIHSS 5 (interquartile range, 4–7), median onset-to-groinpuncturetime320minutes(interquartilerange,237–528minutes).Recanalization(TICI2b–3)wasachievedin26(78.7%) patients. Two cases of symptomatic intracranial hemorrhage were observed. Favorable (mRS 0–2) and moderate (mRS 0–3) clinical outcome at http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores: Recanalization Rates, Periprocedural Complications, and Clinical Outcome

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References (32)

Publisher
American Journal of Neuroradiology
Copyright
© 2016 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A4862
Publisher site
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Abstract

ORIGINAL RESEARCH INTERVENTIONAL Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores: Recanalization Rates, Periprocedural Complications, and Clinical Outcome X J. Pfaff, X C. Herweh, X M. Pham, X S. Scho¨nenberger, X S. Nagel, X P.A. Ringleb, X M. Bendszus, and X M. Mo¨hlenbruch ABSTRACT BACKGROUND AND PURPOSE: Mechanical thrombectomy, in addition to intravenous thrombolysis, has become standard in acute ischemic stroke treatment in patients with large-vessel occlusion in the anterior circulation. However, previous randomized controlled stroke trials were not focused on patients with mild-to-moderate symptoms. Thus, there are limited data for patient selection, prediction of clinical outcome, and occurrence of complications in this patient population. The purpose of this analysis was to assess clinical and interventional data in patients treated with mechanical thrombectomy in case of ischemic stroke with mild-to-moderate symptoms. MATERIALSANDMETHODS: Weperformedaretrospectiveanalysisofaprospectivelycollectedstrokedatabase.Inclusioncriteriawere anterior circulation ischemic stroke treated with mechanical thrombectomy at our institution between September 2010 and October 2015 with an NIHSS score of 8. RESULTS: Of 484 patients, we identified 33 (6.8%) with the following characteristics: median NIHSS 5 (interquartile range, 4–7), median onset-to-groinpuncturetime320minutes(interquartilerange,237–528minutes).Recanalization(TICI2b–3)wasachievedin26(78.7%) patients. Two cases of symptomatic intracranial hemorrhage were observed. Favorable (mRS 0–2) and moderate (mRS 0–3) clinical outcome at

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Nov 1, 2016

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