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P. White, J. Raymond (2008)
Endovascular Coiling of Cerebral Aneurysms Using “Bioactive” or Coated-Coil Technologies: A Systematic Review of the LiteratureAmerican Journal of Neuroradiology, 30
A. Campi, N. Ramzi, A. Molyneux, P. Summers, R. Kerr, M. Sneade, J. Yarnold, J. Rischmiller, J. Byrne (2007)
Retreatment of Ruptured Cerebral Aneurysms in Patients Randomized by Coiling or Clipping in the International Subarachnoid Aneurysm Trial (ISAT)Stroke, 38
David Xu, M. Hurley, H. Batjer, B. Bendok (2010)
Delayed Cranial Nerve Palsy After Coiling of Carotid Cavernous Sinus Aneurysms: Case ReportNeurosurgery, 66
J. Raymond, F. Guilbert, A. Weill, S. Georganos, L. Juravsky, A. Lambert, J. Lamoureux, M. Chagnon, D. Roy (2003)
Long-Term Angiographic Recurrences After Selective Endovascular Treatment of Aneurysms With Detachable CoilsStroke: Journal of the American Heart Association, 34
É. Tollard, T. Darsaut, F. Bing, F. Guilbert, G. Gevry, Jean Raymond (2012)
Outcomes of Endovascular Treatments of Aneurysms: Observer Variability and Implications for Interpreting Case Series and Planning Randomized TrialsAmerican Journal of Neuroradiology, 33
D. Pelz, S. Lownie, A. Fox (1998)
Thromboembolic events associated with the treatment of cerebral aneurysms with Guglielmi detachable coils.AJNR. American journal of neuroradiology, 19 8
S. Coley, M. Sneade, Alison Clarke, Ziyah Mehta, D. Kallmes, S. Cekirge, I. Saatci, D. Roy, A. Molyneux (2012)
Cerecyte Coil Trial: Procedural Safety and Clinical Outcomes in Patients with Ruptured and Unruptured Intracranial AneurysmsAmerican Journal of Neuroradiology, 33
S. Ferns, M. Sprengers, W. Rooij, G. Rinkel, J. Rijn, S. Bipat, M. Sluzewski, C. Majoie (2009)
Coiling of Intracranial Aneurysms: A Systematic Review on Initial Occlusion and Reopening and Retreatment RatesStroke, 40
(1929)
University of Florida (Shands Hospital) University of Virginia Health System
A. Molyneux, R. Kerr, Ly-Mee Yu, M. Clarke, M. Sneade, J. Yarnold, P. Sandercock (2005)
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusionThe Lancet, 366
J. Raymond, A. Molyneux, A. Fox, S. Johnston, J. Collet, I. Rouleau, the group (2008)
The TEAM trial: Safety and efficacy of endovascular treatment of unruptured intracranial aneurysms in the prevention of aneurysmal hemorrhages: A randomized comparison with indefinite deferral of treatment in 2002 patients followed for 10 yearsTrials, 9
Centre Hospitalier Universitaire de Nantes-Hô pital Guillaume et René Laennec
C. McDougall, S. Johnston, Anil Gholkar, S. Barnwell, J. Suarez, J. Romero, J. Chaloupka, A. Bonafé, A. Wakhloo, Donatella Tampieri, C. Dowd, A. Fox, S. Imm, Kirsten Carroll, A. Turk (2014)
Bioactive versus Bare Platinum Coils in the Treatment of Intracranial Aneurysms: The MAPS (Matrix and Platinum Science) TrialAmerican Journal of Neuroradiology, 35
P. White, S. Lewis, H. Nahser, R. Sellar, T. Goddard, A. Gholkar (2008)
HydroCoil Endovascular Aneurysm Occlusion and Packing Study (HELPS Trial): Procedural Safety and Operator-Assessed Efficacy ResultsAmerican Journal of Neuroradiology, 29
O. Naggara, A. Lecler, C. Oppenheim, J. Meder, J. Raymond (2012)
Endovascular treatment of intracranial unruptured aneurysms: a systematic review of the literature on safety with emphasis on subgroup analyses.Radiology, 263 3
P. Meyers, S. Lavine, B. Fitzsimmons, C. Commichau, A. Parra, S. Mayer, R. Solomon, E. Connolly (2004)
Chemical Meningitis after Cerebral Aneurysm Treatment Using Two Second-generation Aneurysm Coils: Report of Two CasesNeurosurgery, 55
T. Becske, D. Kallmes, I. Saatci, C. McDougall, I. Szikora, G. Lanzino, C. Moran, H. Woo, D. Lopes, A. Berez, D. Cher, A. Siddiqui, E. Levy, F. Albuquerque, D. Fiorella, Z. Berentei, M. Marosfoi, S. Cekirge, P. Nelson (2013)
Pipeline for uncoilable or failed aneurysms: results from a multicenter clinical trial.Radiology, 267 3
R. Turner, J. Byrne, M. Kelly, A. Mitsos, V. Gonugunta, Shivu Lalloo, P. Rasmussen, D. Fiorella (2008)
DELAYED VISUAL DEFICITS AND MONOCULAR BLINDNESS AFTER ENDOVASCULAR TREATMENT OF LARGE AND GIANT PARAOPHTHALMIC ANEURYSMSNeurosurgery, 63
H. Cloft, D. Kallmes (2002)
Cerebral aneurysm perforations complicating therapy with Guglielmi detachable coils: a meta-analysis.AJNR. American journal of neuroradiology, 23 10
A. Molyneux (2002)
International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trialThe Lancet, 360
A. Molyneux, Alison Clarke, M. Sneade, Z. Mehta, S. Coley, D. Roy, D. Kallmes, A. Fox (2012)
Cerecyte Coil Trial: Angiographic Outcomes of a Prospective Randomized Trial Comparing Endovascular Coiling of Cerebral Aneurysms With Either Cerecyte or Bare Platinum CoilsStroke, 43
Thanh Nguyen, J. Raymond, F. Guilbert, D. Roy, M. Bérubé, M. Mahmoud, A. Weill (2008)
Association of endovascular therapy of very small ruptured aneurysms with higher rates of procedure-related rupture.Journal of neurosurgery, 108 6
Staff Senate (2005)
The University of Oklahoma Health Sciences Center
LARGE trial and POSITIVE trial, enrolling site for multiple other trials; Payment for Lectures (including service on Speakers Bureaus): Penumbra, MicroVention; Stock/Stock Options: Pulsar Vascular
J. Raymond, D. Roy, P. White, D. Fiorella, R. Chapot, S. Bracard, D. Kallmes (2008)
A Randomized Trial Comparing Platinum and Hydrogel-Coated Coils in Patients Prone to Recurrence after Endovascular Treatment (The PRET Trial)Interventional Neuroradiology, 14
T. Darsaut, J. Findlay, J. Raymond (2011)
The Design of the Canadian UnRuptured Endovascular versus Surgery (CURES) TrialCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 38
Gibbes (1842)
Leeds General InfirmaryProvincial Medical and Surgical Journal, s1-4
Brian O’shaughnessy, C. Getch, B. Bendok, R. Parkinson, H. Batjer (2004)
Progressive growth of a giant dolichoectatic vertebrobasilar artery aneurysm after complete Hunterian occlusion of the posterior circulation: case report.Neurosurgery, 55 5
D. Roy, G. Milot, J. Raymond (2001)
Endovascular Treatment of Unruptured AneurysmsStroke: Journal of the American Heart Association, 32
I. Rezek, R. Lingineni, M. Sneade, A. Molyneux, Allan Fox, D. Kallmes (2014)
Differences in the Angiographic Evaluation of Coiled Cerebral Aneurysms between a Core Laboratory Reader and Operators: Results of the Cerecyte Coil TrialAmerican Journal of Neuroradiology, 35
University of Mississippi Health Care University of Alberta Hospital
LVIS IDE study PI, Sequent WEB IDE trial PI; Patents (planned, pending or issued): Codman/JNJ; Royalties: Codman/JNJ; Travel/Accommodations/Meeting Expenses Unrelated to Activities Listed
R. Replogle (2006)
Rates of Delayed Rebleeding From Intracranial Aneurysms Are Low After Surgical and Endovascular TreatmentStroke, 37
S. Im, M. Han, Bae Kwon, Cheolkyu Jung, J. Kim, Dae Han (2007)
Aseptic meningitis after embolization of cerebral aneurysms using hydrogel-coated coils: report of three cases.AJNR. American journal of neuroradiology, 28 3
P. White, S. Lewis, A. Gholkar, R. Sellar, H. Nahser, C. Cognard, Lynn Forrester, J. Wardlaw (2011)
Hydrogel-coated coils versus bare platinum coils for the endovascular treatment of intracranial aneurysms (HELPS): a randomised controlled trialThe Lancet, 377
(2014)
The design of the Canadian AJNR
J. Raymond (2009)
Counterpoint: Has the Last Word Been Said?American Journal of Neuroradiology, 30
BACKGROUND AND PURPOSE: Some patients with large or recurrent aneurysms may be at increased risk of recurrence postcoiling. The Patients Prone to Recurrence after Endovascular Treatment (PRET) trial was designed to assess whether hydrogel coils were superior to platinum coils in these high-risk patients. This article reports periprocedural safety and operator-assessed angiographic results from the PRET trial. MATERIALS AND METHODS: PRET was a pragmatic, multicenter, randomized controlled trial. Patients had ≥10-mm aneurysms (PRET-1) or a major recurrence after coiling of an aneurysm of any size (PRET-2). Patients were randomly allocated to hydrogel or control arms (any platinum coil) by using concealed allocation with minimization. Assist devices could be used as clinically required. Aneurysms could be unruptured or recently ruptured. Analyses were on an intent-to-treat basis. RESULTS: Four hundred forty-seven patients were recruited (250 PRET-1; 197 PRET-2). Aneurysms were recently ruptured in 29% of PRET-1 and 4% of PRET-2 patients. Aneurysms were ≥10 mm in all PRET-1 and in 50% of PRET-2 patients. They were wide-neck (≥4 mm) in 70% and in the posterior circulation in 24% of patients. Stents were used in 28% of patients (35% in PRET-2). Coiling was successful in 98%. Adverse events occurred in 28 patients with hydrogel and 23 with platinum coils. Mortality ( n = 2, unrelated to treatment) and morbidity (defined as mRS >2 at 1 month) occurred in 25 patients (5.6%; 12 hydrogel, 13 platinum), related to treatment in 10 (4 hydrogel; 6 platinum) (or 2.3% of 444 treated patients). No difference was seen between hydrogel and platinum for any of the indices used to assess safety up to at least 30 days after treatment. At 1 month, 95% of patients were home with a good outcome (mRS ≤2 or unchanged). Operator-assessed angiographic outcomes were satisfactory (complete occlusion or residual neck) in 339 of 447 or 76.4% of patients, with no significant difference between groups. CONCLUSIONS: Endovascular treatment of large and recurrent aneurysms can be performed safely with platinum or hydrogel coils. ABBREVIATIONS: CCT Cerecyte Coil Trial DSMC Data Safety and Monitoring Committee HELPS HydroCoil Endovascular Aneurysm Occlusion and Packing Study MAPS Matrix and Platinum Science PI Principal Investigator PRET Patients Prone to Recurrence after Endovascular Treatment
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Sep 1, 2014
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