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SUMMARY: Measures of cerebral metabolism may be useful in the selection of patients for reperfusion therapies and as end points in clinical trials. However, there are currently no clinically routine techniques that provide such data directly. We review how imaging modalities in current clinical use may provide surrogate markers of metabolic activity. Promising techniques for metabolic imaging that are currently in the pipeline are reviewed. ABBREVIATIONS: MR-COMI cerebral oxygen metabolic index CMRO 2 cerebral metabolic rate for oxygen OCI oxygen challenge imaging OEF oxygen extraction fraction
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Jun 1, 2014
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