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Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features

Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement. Abbreviations ADC apparent diffusion coefficient AT/RT atypical teratoid/rhabdoid tumor CNS central nervous system DWI diffusion-weighted imaging FLAIR fluid-attenuated inversion recovery L left mRNA messenger ribonucleic acid N/A not available ND not depicted OS overall survival PNET primitive neuroectodermal tumor PR partial resection R right TR total resection http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Atypical Teratoid/Rhabdoid Tumors in Adult Patients: CT and MR Imaging Features

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Publisher
American Journal of Neuroradiology
Copyright
Copyright © 2011 by the American Society of Neuroradiology.
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A2361
pmid
21051520
Publisher site
See Article on Publisher Site

Abstract

SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement. Abbreviations ADC apparent diffusion coefficient AT/RT atypical teratoid/rhabdoid tumor CNS central nervous system DWI diffusion-weighted imaging FLAIR fluid-attenuated inversion recovery L left mRNA messenger ribonucleic acid N/A not available ND not depicted OS overall survival PNET primitive neuroectodermal tumor PR partial resection R right TR total resection

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Jan 1, 2011

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