Access the full text.
Sign up today, get DeepDyve free for 14 days.
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
SUMMARY: CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increase in mIns concentration, pointing to gliosis and astrocytic proliferation. Abbreviations a.u. arbitrary unit Cho choline-containing compounds CNS central nervous system Cr creatine/phosphocreatine CTX cerebrotendinous xanthomatosis Lip lipid Lip09 lipid signals at 0.9 ppm Lip13 lipid signals at 1.3 ppm mIns myo-inositol MRS MR spectroscopy NAA N -acetylaspartate PRESS point-resolved spectroscopy sequence STEAM short echo time stimulated echo acquisition mode VOI volume of interest
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Aug 1, 2010
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.