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Diffusion-Weighted Echo-Planar MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of Different Histologic Subtypes Possible?

Diffusion-Weighted Echo-Planar MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of... This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1412v1 30/3/591 most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Habermann, C.R. Articles by Jaehne, M. Search for Related Content PubMed PubMed Citation Articles by Habermann, C.R. Articles by Jaehne, M. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 30:591-596, March 2009 © 2009 American Society of Neuroradiology HEAD & NECK Diffusion-Weighted Echo-Planar MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of Different Histologic Subtypes Possible? C.R. Habermann a , C. Arndt a , J. Graessner d , L. Diestel a , K.U. Petersen b , F. Reitmeier c , J.O. Ussmueller e , G. Adam a and M. Jaehne c a Department of Diagnostic and Interventional Radiology, Diagnostic Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany b Department of Psychiatry and Psychotherapy, Center of Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany c Department of Oto-, Rhino-, Laryngology, Center for Head Care and Dermatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany d Siemens Healthcare, Hamburg, Germany e Center of Oto-, Rhino-, Laryngology Regensburg, Regensburg, Germany Please address correspondence to Christian R. Habermann, MD, University Medical Center, Diagnostic Center, Department of Diagnostic and Interventional Radiology, Martinistr. 52, 20246 Hamburg, Germany; e-mail: c.habermann@uke.uni-hamburg.de BACKGROUND AND PURPOSE: Our aim was to determine the value of echo-planar diffusion-weighted MR imaging (epiDWI) in differentiating various types of primary parotid gland tumors. MATERIALS AND METHODS: One hundred forty-nine consecutive patients with suspected tumors of the parotid gland were examined with an epiDWI sequence by using a 1.5T unit. Image analysis was performed by 2 radiologists independently, and the intraclass correlation coefficient was computed. Histologic diagnosis was obtained in every patient. For comparison of apparent diffusion coefficients (ADCs), a paired 2-tailed Student t test with a Bonferroni correction was used. RESULTS: In 136 patients, a primary parotid gland tumor was confirmed by histology. Among the observers, a high correlation was calculated (0.98). ADC values of pleomorphic adenomas were significantly higher than those of all other entities, except for myoepithelial adenomas ( P = .054). ADC values of Warthin tumors were different from those of myoepithelial adenomas, lipomas, and salivary duct carcinomas ( P < .001, 0.013, and .037, respectively). Mucoepidermoid carcinomas, acinic cell carcinomas, and basal cell adenocarcinomas were not differentiable from Warthin tumors ( P = .094, .396, and .604, respectively). CONCLUSION: epiDWI has the potential to differentiate pleomorphic adenoma and myoepithelial adenomas from all other examined entities. Due to an overlap not only within the group of benign and malignant lesions but also between groups, diagnoses should not be addressed on the basis of ADC values solely. Therefore, further studies combining DWI, morphologic criteria, and probably other MR imaging techniques seem warranted. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Diffusion-Weighted Echo-Planar MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of Different Histologic Subtypes Possible?

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References (40)

Publisher
American Journal of Neuroradiology
Copyright
Copyright © 2010 by the American Society of Neuroradiology.
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A1412
Publisher site
See Article on Publisher Site

Abstract

This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1412v1 30/3/591 most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Habermann, C.R. Articles by Jaehne, M. Search for Related Content PubMed PubMed Citation Articles by Habermann, C.R. Articles by Jaehne, M. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 30:591-596, March 2009 © 2009 American Society of Neuroradiology HEAD & NECK Diffusion-Weighted Echo-Planar MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of Different Histologic Subtypes Possible? C.R. Habermann a , C. Arndt a , J. Graessner d , L. Diestel a , K.U. Petersen b , F. Reitmeier c , J.O. Ussmueller e , G. Adam a and M. Jaehne c a Department of Diagnostic and Interventional Radiology, Diagnostic Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany b Department of Psychiatry and Psychotherapy, Center of Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany c Department of Oto-, Rhino-, Laryngology, Center for Head Care and Dermatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany d Siemens Healthcare, Hamburg, Germany e Center of Oto-, Rhino-, Laryngology Regensburg, Regensburg, Germany Please address correspondence to Christian R. Habermann, MD, University Medical Center, Diagnostic Center, Department of Diagnostic and Interventional Radiology, Martinistr. 52, 20246 Hamburg, Germany; e-mail: c.habermann@uke.uni-hamburg.de BACKGROUND AND PURPOSE: Our aim was to determine the value of echo-planar diffusion-weighted MR imaging (epiDWI) in differentiating various types of primary parotid gland tumors. MATERIALS AND METHODS: One hundred forty-nine consecutive patients with suspected tumors of the parotid gland were examined with an epiDWI sequence by using a 1.5T unit. Image analysis was performed by 2 radiologists independently, and the intraclass correlation coefficient was computed. Histologic diagnosis was obtained in every patient. For comparison of apparent diffusion coefficients (ADCs), a paired 2-tailed Student t test with a Bonferroni correction was used. RESULTS: In 136 patients, a primary parotid gland tumor was confirmed by histology. Among the observers, a high correlation was calculated (0.98). ADC values of pleomorphic adenomas were significantly higher than those of all other entities, except for myoepithelial adenomas ( P = .054). ADC values of Warthin tumors were different from those of myoepithelial adenomas, lipomas, and salivary duct carcinomas ( P < .001, 0.013, and .037, respectively). Mucoepidermoid carcinomas, acinic cell carcinomas, and basal cell adenocarcinomas were not differentiable from Warthin tumors ( P = .094, .396, and .604, respectively). CONCLUSION: epiDWI has the potential to differentiate pleomorphic adenoma and myoepithelial adenomas from all other examined entities. Due to an overlap not only within the group of benign and malignant lesions but also between groups, diagnoses should not be addressed on the basis of ADC values solely. Therefore, further studies combining DWI, morphologic criteria, and probably other MR imaging techniques seem warranted. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Mar 1, 2009

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