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This Article Figures Only Full Text Full Text (PDF) Supplemental Online Figure All Versions of this Article: ajnr.A1302v1 30/1/46 most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Habibi, R. Articles by Finn, J.P. Search for Related Content PubMed PubMed Citation Articles by Habibi, R. Articles by Finn, J.P. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 30:46-52, January 2009 © 2009 American Society of Neuroradiology HEAD & NECK High-Resolution 3T MR Angiography of the Carotid Arteries: Comparison of Manual and Semiautomated Quantification of Stenosis R. Habibi a , M.M. Lell a , R. Steiner c , S.G. Ruehm a , J.W. Sayre a ,b , K. Nael a and J.P. Finn a a Department of Radiological Sciences, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, Calif b Department of Biostatistics, UCLA School of Public Health, Los Angeles, Calif c Department of Radiology, University Erlangen, Erlangen, Germany Please address correspondence to: Reza Habibi, MD, Department of Radiology, David Geffen School of Medicine at UCLA, Peter V. Ueberroth Bldg, Ste 3371, 10945 Le Conte Ave, Los Angeles, CA 90095; e-mail: Rhabibi@mednet.ucla.edu BACKGROUND AND PURPOSE: High-resolution contrast-enhanced MR angiography (CE-MRA) acquired at 3T exquisitely depict carotid artery (CA) stenosis. In this study, we examined the agreement of different vessel-analysis tools with manual quantitative measurement by 2 readers using CE-MRA data. MATERIALS AND METHODS: Three vessel tools determining the trajectory of the vessel of interest and, subsequently, the vessel dimensions were tested against manual measurements. Diameter and area stenoses were calculated. CE-MRA data of 32 patients with CA stenosis were evaluated. The agreement between different measurements was assessed with statistics after categorizing stenosis (<25%, 25%–49%, 50%–69%, 70%–99%, and 100%). RESULTS: The mean grades of stenosis based on diameter measurements were 59% (readers) and 60%/56%/59% based on the analysis with tools A/B/C ( P = 0.2–0.7). values for agreement between readers and the vessel tools were 0.73/0.77/0.77 (tools A/B/C for all CAs) and 0.66/0.74/0.75 (for the symptomatic side). The mean grades of stenoses based on area measurements for tools A/B/C were 68%/63%/69% versus 58% for readers. Values from readers differed significantly from those for tools A and C ( P < 0.01). values for agreement between readers and the vessel tools were 0.66/0.55/0.64 (for all CAs) and 0.53/0.44/0.57 (for the symptomatic side). CONCLUSIONS: The automated approach allows accurate assessment of vessel dimensions in MRA images at least for diameter measurements according to the North American Symptomatic Carotid Endarterectomy Trial criteria. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Jan 1, 2009
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