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This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Lell, M.M. Articles by Villablanca, J.P. Search for Related Content PubMed PubMed Citation Articles by Lell, M.M. Articles by Villablanca, J.P. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 28:1362-1368, August 2007 DOI 10.3174/ajnr.A0558 © 2007 American Society of Neuroradiology HEAD & NECK Bone-Subtraction CT Angiography: Evaluation of Two Different Fully Automated Image-Registration Procedures for Interscan Motion Compensation M.M. Lell a , H. Ditt b , C. Panknin a ,b , J.W. Sayre a ,c , S.G. Ruehm a , E. Klotz b , B.F. Tomandl d and J.P. Villablanca a a Department of Radiological Sciences, David Geffen School of Medicine at the University of California, Los Angeles, Calif b Siemens Medical Solutions, Forchheim, Germany c Department of Biostatistics, the University of California, Los Angeles School of Public Health, Los Angeles, Calif d Department of Neuroradiology, Klinikum Bremen-Mitte, Bremen, Germany Please address correspondence to Michael Lell, MD, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Peter V. Ueberroth Bldg, Suite 3371, 10945 LeConte Ave, Los Angeles, CA 90095; e-mail: Michael.Lell@idr.med.uni-erlangen.de BACKGROUND AND PURPOSE: Bone-subtraction techniques have been shown to enhance CT angiography (CTA) interpretation, but motion can lead to incomplete bone removal. The aim of this study was to evaluate 2 novel registration techniques to compensate for patient motion. MATERIALS AND METHODS: Fifty-four patients underwent bone-subtraction CTA (BSCTA) for the evaluation of the neck vessels with 64-section CT. We tested 3 different registration procedures: pure rigid registration (BSCTA), slab-based registration (SB-BSCTA), and a partially rigid registration (PR-BSCTA) approach. Subtraction quality for the assessment of different vascular segments was evaluated by 2 examiners in a blinded fashion. The Cohen kappa test was applied for interobserver variability, and the Wilcoxon signed rank test, for differences between the procedures. Motion between the corresponding datasets was measured and plotted against image-quality scores. RESULTS: Algorithms with motion compensation revealed higher image-quality scores (SB-BSCTA, mean 4.31; PR-BSCTA, mean 4.43) than pure rigid registration (BSCTA, mean 3.88). PR-BSCTA was rated superior to SB-BSCTA for the evaluation of the cervical internal and external carotid arteries ( P < .001), whereas there was no significant difference for the other vessels ( P = .157–.655). Both algorithms were clearly superior to pure rigid registration for all vessels except the basilar and ophthalmic artery. Interobserver agreement was high ( = 0.46–0.98). CONCLUSION: Bone-subtraction algorithms with motion compensation provided higher image-quality scores than pure rigid registration methods, especially in cases with complex motion. PR-BSCTA was rated superior to SB-BSCTA in the visualization of the internal and external carotid arteries. This article has been cited by other articles: C.-W. Lee, A. Huang, Y.-H. Wang, C.-Y. Yang, Y.-F. Chen, and H.-M. Liu Intracranial Dural Arteriovenous Fistulas: Diagnosis and Evaluation with 64-Detector Row CT Angiography Radiology, July 1, 2010; 256(1): 219 - 228. Abstract Full Text PDF C. Thomas, A. Korn, D. Ketelsen, S. Danz, I. Tsifikas, C. D. Claussen, U. Ernemann, and M. Heuschmid Automatic Lumen Segmentation in Calcified Plaques: Dual-Energy CT Versus Standard Reconstructions in Comparison With Digital Subtraction Angiography Am. J. Roentgenol., June 1, 2010; 194(6): 1590 - 1595. Abstract Full Text PDF D. Gandhi, A. Pandey, S.A. Ansari, J.J. Gemmete, B.G. Thompson Jr, and S.K. Mukherji Multi-Detector Row CT Angiography with Direct Intra-Arterial Contrast Injection for the Evaluation of Neurovascular Disease: Technique, Applications, and Initial Experience AJNR Am. J. Neuroradiol., May 1, 2009; 30(5): 1054 - 1058. Abstract Full Text PDF Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Aug 1, 2007
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