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Determination of Potassium by Dry Reagent Carrier Technology: A Multicentre Evaluation

Determination of Potassium by Dry Reagent Carrier Technology: A Multicentre Evaluation Introduction Paschen et al.: Determination of K + by dry reagent carrier The determination of potassium in serum or plasma is important in emergency cases and for monitoring dyskalaemia and its therapy. Both hyperkalaemia or hypokalaemia, if severe, are dangerous, and must be treated immediately. The commonly used methods for the determination of potassium concentrations are flame atomic emission spectrometry (FAES) and potentiometric measurements with ion selective electrodes (ISE). The relatively expensive instruments required are standard equipment in every clinical laboratory, but not in the physician's office. The laboratories are, however, frequently too far away from the office to perform potassium determinations in emergency situations. To allow simple, reliable, and quick potassium determinations in the physician's office a test based on dry reagent carrier technology was developed (1). The recently developed dry reagent carrier Reflotron® K4" employs a new technology for potassium determination by using a valinomycin-coupled colour reaction. It completes the analyte menu of the Reflotron® system for the quantitative analysis of clinicochemical analytes in undiluted samples. The basic chemical reaction and the construction of the dry reagent carrier of the new test are described here together with the results of a multicentre evaluation. Test Principle of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Chemistry and Laboratory Medicine de Gruyter

Determination of Potassium by Dry Reagent Carrier Technology: A Multicentre Evaluation

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Publisher
de Gruyter
Copyright
Copyright © 2009 Walter de Gruyter
ISSN
1434-6621
eISSN
1437-4331
DOI
10.1515/cclm.1993.31.8.545
Publisher site
See Article on Publisher Site

Abstract

Introduction Paschen et al.: Determination of K + by dry reagent carrier The determination of potassium in serum or plasma is important in emergency cases and for monitoring dyskalaemia and its therapy. Both hyperkalaemia or hypokalaemia, if severe, are dangerous, and must be treated immediately. The commonly used methods for the determination of potassium concentrations are flame atomic emission spectrometry (FAES) and potentiometric measurements with ion selective electrodes (ISE). The relatively expensive instruments required are standard equipment in every clinical laboratory, but not in the physician's office. The laboratories are, however, frequently too far away from the office to perform potassium determinations in emergency situations. To allow simple, reliable, and quick potassium determinations in the physician's office a test based on dry reagent carrier technology was developed (1). The recently developed dry reagent carrier Reflotron® K4" employs a new technology for potassium determination by using a valinomycin-coupled colour reaction. It completes the analyte menu of the Reflotron® system for the quantitative analysis of clinicochemical analytes in undiluted samples. The basic chemical reaction and the construction of the dry reagent carrier of the new test are described here together with the results of a multicentre evaluation. Test Principle of

Journal

Clinical Chemistry and Laboratory Medicine – de Gruyter

Published: Jan 1, 1993

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