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D. Parker, A. Key, R. Davies, J. Scopes, H. Marcovitch (1971)
A disposable catheter-tip transducer for continuous measurement of blood oxygen tension in vivo.Biomedical engineering, 6 7
P. Eberhard Bioelectronics Department, F. Hoff man n-La Röche &Co Ltd, Basel/Switzerland Since the introduction of the technique of cutaneous pO measurement by directly heated oxygen sensors in 1972 [l, 2] , the clinical applications of this new method have been extensively investigated and described in numerous papers. Although the method has proven to be of considerable interest for neonatal monitoring , the limitations of this method have not been fully explored until now. In this paper, some methodological criteria for the assessment of the reliability of cutaneotis pO monitoring are discussed. 1.) Oxygen profile in the vicinity of the cathode In contrast to conventional Clark-type oxygen Sensors in which the cathode diameter is kept small, in our skin sensor [3] a large cathode (diameter k mm) is used to obtain an average pO value over a sufficiently large skin area. The permeability of the membrane for oxygen has to be kept low to avoid a disturbance of the oxygen profile in the skin äs a result of the consumption of the sensor. The skin consists essentially of two different layers, (a) the epidermis, an avascular superficial layer, 20 to lUOO ym thick and underneath (b) the dermis,
Biomedizinische Technik / Biomedical Engineering – de Gruyter
Published: Jan 1, 1976
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