Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Nieuwdorp, H. Mooij, Jojanneke Kroon, B. Atasever, J. Spaan, C. Ince, F. Holleman, M. Diamant, R. Heine, J. Hoekstra, J. Kastelein, E. Stroes, H. Vink (2006)
Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes.Diabetes, 55 4
T. Osicka, Christine Houlihan, James Chan, G. Jerums, W. Comper (2000)
Albuminuria in patients with type 1 diabetes is directly linked to changes in the lysosome-mediated degradation of albumin during renal passage.Diabetes, 49 9
So-Young Lee, Mary Choi (2015)
Urinary biomarkers for early diabetic nephropathy: beyond albuminuriaPediatric Nephrology, 30
M. Vestra, A. Saller, E. Bortoloso, Michael Mauer, Paola Fioretto (2000)
Structural involvement in type 1 and type 2 diabetic nephropathy.Diabetes & metabolism, 26 Suppl 4
M. Cooper (1996)
Renal protection and angiotensin converting enzyme inhibition in microalbuminuric type I and type II diabetic patientsJournal of Hypertension, 14
J. Eyre, Kyriakos Ioannou, B. Grubb, M. Saleem, P. Mathieson, N. Brunskill, E. Christensen, P. Topham (2007)
Statin-sensitive endocytosis of albumin by glomerular podocytes.American journal of physiology. Renal physiology, 292 2
A. Sands, B. Zambrowicz, J. Rosenstock, P. Lapuerta, B. Bode, S. Garg, J. Buse, Phillip Banks, R. Heptulla, M. Rendell, W. Cefalu, P. Strumph (2015)
Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 DiabetesDiabetes Care, 38
S. Soni, S. Gowrishankar, A. Kishan, A. Raman (2006)
Non diabetic renal disease in type 2 diabetes mellitusNephrology, 11
B. Mackinnon, L. Shakerdi, C. Deighan, J. Fox, D. O’Reilly, M. Boulton-Jones (2003)
Urinary transferrin, high molecular weight proteinuria and the progression of renal disease.Clinical nephrology, 59 4
C. Mogensen, C. Christensen, E. Vittinghus (1983)
The Stages in Diabetic Renal Disease: With Emphasis on the Stage of Incipient Diabetic NephropathyDiabetes, 32
B. Brenner, T. Meyer, T. Hostetter (1982)
Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease.The New England journal of medicine, 307 11
Morrisey, Steadman, Williams, Phillips (1999)
Renal proximal tubular cell fibronectin accumulation in response to glucose is polyol pathway dependentKidney international, 55 6
C., Hyung Park, T. Maack (1984)
Albumin absorption and catabolism by isolated perfused proximal convoluted tubules of the rabbit.The Journal of clinical investigation, 73 3
P Fioretto, M Mauer, E Brocco (1996)
Patterns of renal injury in Type 2 (non-insulin-dependent) diabetic patients with microalbuminuriaDiabetologia, 39
T. Deckert, B. Feldt-Rasmussen, K. Borch-Johnsen, T. Jensen, A. Kofoed‐Enevoldsen (1989)
Albuminuria reflects widespread vascular damageDiabetologia, 32
H. Parving, H. Parving, J. Lewis, M. Ravid, G. Remuzzi, L. Hunsicker (2006)
Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: a global perspective.Kidney international, 69 11
Fawn Wolf (2016)
Standards of Medical Care in Diabetes—2016 Abridged for Primary Care ProvidersClinical Diabetes : A Publication of the American Diabetes Association, 34
Maria Narres, H. Claessen, S. Droste, T. Kvitkina, M. Koch, O. Kuss, A. Icks (2016)
The Incidence of End-Stage Renal Disease in the Diabetic (Compared to the Non-Diabetic) Population: A Systematic ReviewPLoS ONE, 11
N. Robles, J. Villa, R. Gallego (2015)
Non-Proteinuric Diabetic NephropathyJournal of Clinical Medicine, 4
V Vallon, KA Platt, R Cunard (2011)
SGLT2 mediates glucose reabsorption in the early proximal tubuleJ Am Soc Nephrol, 22
Temesgen Fiseha (2015)
Urinary biomarkers for early diabetic nephropathy in type 2 diabetic patientsBiomarker Research, 3
B. Perkins, Linda Ficociello, K. Silva, D. Finkelstein, J. Warram, A. Krolewski (2003)
Regression of microalbuminuria in type 1 diabetes.The New England journal of medicine, 348 23
O. Gheith, Nashwa Farouk, N. Nampoory, M. Halim, T. Al-Otaibi (2015)
Diabetic kidney disease: world wide difference of prevalence and risk factorsJournal of Nephropharmacology, 5
Kdoqi (2007)
KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease.American journal of kidney diseases : the official journal of the National Kidney Foundation, 49 2 Suppl 2
Jean-Michel Halimi (2012)
The emerging concept of chronic kidney disease without clinical proteinuria in diabetic patients.Diabetes & metabolism, 38 4
(2014)
Standards of medical care in diabetes-2014Diabetes Care, 37
Michael Gekle (2007)
Renal albumin handling: a look at the dark side of the filter.Kidney international, 71 6
Gabriela Orasanu, J. Plutzky (2009)
The pathologic continuum of diabetic vascular disease.Journal of the American College of Cardiology, 53 5 Suppl
S. Olsen (1999)
Identification of non-diabetic glomerular disease in renal biopsies from diabetics--a dilemma.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 14 8
(2013)
2002 MRC / BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 , 536 high - risk individuals : a randomised placebo - controlled trial
C. Mogensen, C. Christensen (1984)
Predicting diabetic nephropathy in insulin-dependent patients.The New England journal of medicine, 311 2
Anuradha Kalani, A. Mohan, M. Godbole, E. Bhatia, Amit Gupta, Raj Sharma, Swasti Tiwari (2013)
Wilm's Tumor-1 Protein Levels in Urinary Exosomes from Diabetic Patients with or without ProteinuriaPLoS ONE, 8
HH Parving (1996)
Microalbuminuria in essential hypertension and diabetesJ Hypertens, 14
Syed Haque, G. Ariceta, D. Batlle (2012)
Proximal renal tubular acidosis: a not so rare disorder of multiple etiologiesNephrology Dialysis Transplantation, 27
Anushka Patel, S. MacMahon, J. Chalmers, B. Neal, L. Billot, M. Woodward, M. Marre, M. Cooper, P. Glasziou, D. Grobbee, P. Hamet, S. Harrap, S. Heller, Li-sheng Liu, G. Mancia, C. Mogensen, C. Pan, N. Poulter, A. Rodgers, B. Williams, Severine Bompoint, B. Galan, R. Joshi, F. Travert (2008)
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.The New England journal of medicine, 358 24
C. Mogensen, C. Christensen (1984)
[Predicting diabetic nephropathy].Journees annuelles de diabetologie de l'Hotel-Dieu
H. Parving (1996)
Microalbuminuria in essential hypertension and diabetes mellitusJournal of Hypertension, 14
P. Zürbig, G. Jerums, P. Hovind, R. MacIsaac, H. Mischak, S. Nielsen, S. Panagiotopoulos, F. Persson, P. Rossing (2012)
Urinary Proteomics for Early Diagnosis in Diabetic NephropathyDiabetes, 61
H. Heerspink, B. Perkins, D. Fitchett, M. Husain, D. Cherney (2016)
Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications.Circulation, 134 10
R. Brenner, D. Spring, A. Sebastian, E. McSherry, H. Genant, A. Palubinskas, R. Morris (1982)
Incidence of radiographically evident bone disease, nephrocalcinosis, and nephrolithiasis in various types of renal tubular acidosis.The New England journal of medicine, 307 4
J. Prakash, T. Gupta, S. Prakash, P. Bhushan, Usha, M. Sivasankar, Shivendra Singh (2015)
Non-diabetic renal disease in type 2 diabetes mellitus: Study of renal - retinal relationshipIndian Journal of Nephrology, 25
G. Penno, A. Solini, E. Bonora, C. Fondelli, E. Orsi, G. Zerbini, R. Trevisan, M. Vedovato, G. Gruden, F. Cavalot, M. Cignarelli, L. Laviola, S. Morano, A. Nicolucci, G. Pugliese (2011)
Clinical significance of nonalbuminuric renal impairment in type 2 diabetesJournal of Hypertension, 29
L. Russo, R. Sandoval, M. McKee, T. Osicka, A. Collins, Dennis Brown, B. Molitoris, B. Molitoris, W. Comper (2007)
The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states.Kidney international, 71 6
Akihiro Tojo, Hitoshi Endou (1992)
Intrarenal handling of proteins in rats using fractional micropuncture technique.The American journal of physiology, 263 4 Pt 2
H. Castrop, I. Schiessl (2017)
Novel routes of albumin passage across the glomerular filtration barrierActa Physiologica, 219
H. Colhoun, D. Betteridge, P. Durrington, G. Hitman, H. Neil, S. Livingstone, M. Thomason, M. Mackness, V. Charlton-menys, J. Fuller (2004)
Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trialThe Lancet, 364
H. Birn, E. Christensen (2006)
Renal albumin absorption in physiology and pathology.Kidney international, 69 3
G. Lippi, M. Plebani (2017)
Statins for Primary Prevention of Cardiovascular Disease.Trends in pharmacological sciences, 38 2
I. Boer, T. Rue, Y. Hall, P. Heagerty, N. Weiss, J. Himmelfarb (2011)
Temporal trends in the prevalence of diabetic kidney disease in the United States.JAMA, 305 24
JM Stevenson (1995)
Is parental hypertension a risk factor for the development of nephropathy in type 1 diabetes?Nephrol Dial Transplant, 10
P. Jong, J. Heeg, A. Apperloo, D. Zeeuw (1992)
The antiproteinuric effects of blood pressure-lowering agents: differences between nondiabetics and diabetics.Journal of cardiovascular pharmacology, 19 Suppl 6
R. Bilous (2012)
KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update.American journal of kidney diseases : the official journal of the National Kidney Foundation, 60 5
A. Adler, R. Stevens, S. Manley, R. Bilous, C. Cull, R. Holman (2003)
Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64).Kidney international, 63 1
P. Fioretto, A. Zambon, M. Rossato, L. Busetto, R. Vettor (2016)
SGLT2 Inhibitors and the Diabetic KidneyDiabetes Care, 39
B. Perkins, Linda Ficociello, B. Roshan, J. Warram, A. Krolewski (2010)
In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria.Kidney international, 77 1
A. Levey, D. Weiner (2007)
The challenges of the next 5 years.American journal of kidney diseases : the official journal of the National Kidney Foundation, 49 1
K. Alsaad, A. Herzenberg (2007)
Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an updateJournal of Clinical Pathology, 60
P. Ballmer (2001)
Causes and mechanisms of hypoalbuminaemia.Clinical nutrition, 20 3
J. Weening, C. Guldener, M. Daha, N. Klar, A. Wal, F. Prins (1987)
The pathophysiology of protein-overload proteinuria.The American journal of pathology, 129 1
T. Narita, H. Sasaki, Mihoko Hosoba, T. Miura, Naomi Yoshioka, Tsukasa Morii, Takashi Shimotomai, J. Koshimura, H. Fujita, M. Kakei, S. Ito (2004)
Parallel increase in urinary excretion rates of immunoglobulin G, ceruloplasmin, transferrin, and orosomucoid in normoalbuminuric type 2 diabetic patients.Diabetes care, 27 5
M. Manaviat, Mohammad Afkhami, M. Shoja (2004)
Retinopathy and microalbuminuria in type II diabetic patientsBMC Ophthalmology, 4
V. Fonseca, N. Clark (2006)
Standards of Medical Care in Diabetes: Response to PowerDiabetes Care, 29
A. Friedman (2004)
High-protein diets: potential effects on the kidney in renal health and disease.American journal of kidney diseases : the official journal of the National Kidney Foundation, 44 6
G. Jerums, T. Allen, D. Campbell, D. Campbell, Mark Cooper, Richard Gilbert, Richard Gilbert, J. Hammond, J. Hammond, R. O’Brien, R. O’Brien, J. Raffaele, J. Raffaele, C. Tsalamandris (2004)
Long‐term renoprotection by perindopril or nifedipine in non‐hypertensive patients with Type 2 diabetes and microalbuminuriaDiabetic Medicine, 21
Jan Jensen, Knut Borch-Johnsen, Gorm Jensen, Bo Feldt-Rasmussen (1995)
Microalbuminuria reflects a generalized transvascular albumin leakiness in clinically healthy subjects.Clinical science, 88 6
Belinda Jim, M. Ghanta, A. Qipo, Ying Fan, Peter Chuang, H. Cohen, M. Abadi, David Thomas, J. He (2012)
Dysregulated Nephrin in Diabetic Nephropathy of Type 2 Diabetes: A Cross Sectional StudyPLoS ONE, 7
Roberto Bigazzi, S. Bianchi, D. Baldari, V. Campese (1998)
Microalbuminuria predicts cardiovascular events and renal insufficiency in patients with essential hypertensionJournal of Hypertension, 16
Landon Dickson, M. Wagner, R. Sandoval, B. Molitoris (2014)
The proximal tubule and albuminuria: really!Journal of the American Society of Nephrology : JASN, 25 3
A. King, A. Levey (1993)
Dietary protein and renal function.Journal of the American Society of Nephrology : JASN, 3 11
E. Chao (2014)
SGLT-2 Inhibitors: A New Mechanism for Glycemic ControlClinical Diabetes, 32
A. Verhulst, P. D'Haese, M. Broe (2004)
Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells.Journal of the American Society of Nephrology : JASN, 15 9
J. Sidaway, R. Davidson, F. McTaggart, T. Orton, R. Scott, Graham Smith, N. Brunskill (2004)
Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells.Journal of the American Society of Nephrology : JASN, 15 9
H. Parving, H. Parving, M. Gall, M. Gall, P. Skøtt, P. Skøtt, H. Jorgensen, H. Jorgensen, H. Løkkegaard, H. Løkkegaard, Finn Jørgensen, Finn Jørgensen, Bent Nielsen, Bent Nielsen, S. Larsen, S. Larsen (1992)
Prevalence and causes of albuminuria in non-insulin-dependent diabetic patients.Kidney international, 41 4
Jacques Poortmans, Olivier Dellalieux (2000)
Do regular high protein diets have potential health risks on kidney function in athletes?International journal of sport nutrition and exercise metabolism, 10 1
J. Carson, K. Okamura, H. Wakashin, K. Mcfann, E. Dobrinskikh, J. Kopp, J. Blaine (2014)
Podocytes Degrade Endocytosed Albumin Primarily in LysosomesPLoS ONE, 9
Andrew Hall, Paul Bass, Robert Unwin (2014)
Drug-induced renal Fanconi syndrome.QJM : monthly journal of the Association of Physicians, 107 4
G. Strippoli, C. Bonifati, M. Craig, S. Navaneethan, J. Craig (2006)
Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease.The Cochrane database of systematic reviews, 4
Anu Pätäri, C. Forsblom, M. Havana, H. Taipale, P. Groop, H. Holthöfer (2003)
Nephrinuria in diabetic nephropathy of type 1 diabetes.Diabetes, 52 12
S Olsen, CE Mogensen (1996)
How often is NIDDM complicated with non-diabetic renal disease? An analysis of renal biopsies and the literatureDiabetologia, 39
J. Nielsen, K. McNagny (2009)
The role of podocalyxin in health and disease.Journal of the American Society of Nephrology : JASN, 20 8
Peter Lemon (2009)
Is increased dietary protein necessary or beneficial for individuals with a physically active lifestyle?Nutrition reviews, 54 4 Pt 2
A. Martínez-Castelao, J. Navarro-González, J. Górriz, F. Álvaro (2015)
The Concept and the Epidemiology of Diabetic Nephropathy Have Changed in Recent YearsJournal of Clinical Medicine, 4
Steen Olsen, C. Mogensen (1996)
How often is NIDDM complicated with non-diabetic renal disease? An analysis of renal biopsies and the literatureDiabetologia, 39
G. Viberti, R. Jarrett, U. Mahmud, R. Hill, A. Argyropoulos, H. Keen (1982)
MICROALBUMINURIA AS A PREDICTOR OF CLINICAL NEPHROPATHY IN INSULIN-DEPENDENT DIABETES MELLITUSThe Lancet, 319
M. Hara, K. Yamagata, Y. Tomino, A. Saito, Y. Hirayama, Shinya Ogasawara, H. Kurosawa, Sakari Sekine, K. Yan (2012)
Urinary podocalyxin is an early marker for podocyte injury in patients with diabetes: establishment of a highly sensitive ELISA to detect urinary podocalyxinDiabetologia, 55
V. Vallon (2011)
The proximal tubule in the pathophysiology of the diabetic kidney.American journal of physiology. Regulatory, integrative and comparative physiology, 300 5
Merlin Thomas (2014)
Renal effects of dapagliflozin in patients with type 2 diabetesTherapeutic Advances in Endocrinology and Metabolism, 5
R. Ross (1986)
The pathogenesis of atherosclerosis--an update.The New England journal of medicine, 314 8
E. Brocco, Paola Fioretto, Michael Mauer, A. Saller, A. Carraro, F. Frigato, M. Corona, L. Bianchi, Bruno Baggio, Mario Maioli, C. Abaterusso, M. Velussi, M. Sambataro, Flavio Virgili, E. Ossi, R. Nosadini (1997)
Renal structure and function in non-insulin dependent diabetic patients with microalbuminuria.Kidney international. Supplement, 63
R. Glassock (2010)
Is the Presence of Microalbuminuria a Relevant Marker of Kidney Disease?Current Hypertension Reports, 12
Kirtee Raparia, Irtaza Usman, Y. Kanwar (2013)
Renal morphologic lesions reminiscent of diabetic nephropathy.Archives of pathology & laboratory medicine, 137 3
A. Popławska-Kita, Beata Mierzejewska-Iwanowska, M. Szelachowska, K. Siewko, A. Nikołajuk, I. Kinalska, M. Górska (2008)
Glycosaminoglycans urinary excretion as a marker of the early stages of diabetic nephropathy and the disease progressionDiabetes/Metabolism Research and Reviews, 24
J. Stephenson (1995)
Is parental hypertension a risk factor for the development of nephropathy in IDDM.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 10 4
N. Kim, J. Oh, J. Seo, K. Lee, S. Kim, K. Choi, S. Baik, D. Choi, Y. Kang, S. Han, K. Han, Yi-Hwa Ji, D. Cha (2005)
Vascular endothelial growth factor (VEGF) and soluble VEGF receptor FLT-1 in diabetic nephropathy.Kidney international, 67 1
(2016)
Prevalence, Patient Characteristics, and Treatment Mo
Romero-Aroca Pedro, Sagarra-Alamo Ramon, Baget-Bernaldiz Marc, Fernández-Ballart Juan, Mendez Isabel (2010)
Prevalence and Relationship Between Diabetic Retinopathy and Nephropathy, and its Risk Factors in the North-East of Spain, a Population-Based StudyOphthalmic Epidemiology, 17
S. Thomson, A. Deng, Dingjiu Bao, Joseph Satriano, R. Blantz, Volker Vallon (2001)
Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes.The Journal of clinical investigation, 107 2
A. Tojo, S. Kinugasa (2012)
Mechanisms of Glomerular Albumin Filtration and Tubular ReabsorptionInternational Journal of Nephrology, 2012
T Deckert, B Feldt-rasmussen, K Borch-Johnsen, T Jensen, A Kofoed-Enevoldsen (1989)
Albumunuria reflects underspread vascular damage: the steno hypothesisDiabetelogia, 32
V. Vallon, J. Schroth, K. Platt, J. Whaley, S. Thomson, T. Rieg (2010)
SGLT2 mediates glucose reabsorption in the early proximal tubuleThe FASEB Journal, 24
P. Fioretto, M. Mauer, E. Brocco, M. Velussi, F. Frigato, B. Muollo, M. Sambataro, C. Abaterusso, B. Baggio, G. Crepaldi, R. Nosadini (1996)
Patterns of renal injury in NIDDM patients with microalbuminuriaDiabetologia, 39
D. Bliss, D. Brewer (1985)
Increased albumin and normal dextran clearances in protein-overload proteinuria in the rat.Clinical science, 69 3
Ryan Lee, T. Wong, C. Sabanayagam (2015)
Epidemiology of diabetic retinopathy, diabetic macular edema and related vision lossEye and Vision, 2
C. Forsblom, M. Havana, H. Taipale, P. Groop (2003)
Nephrinuria in Diabetic Nephropathy of Type 1
Diabetic nephropathy is defined as a microvascular complication of the kidneys induced by diabetes mellitus and is characterized by albuminuria and progressive loss of kidney function. However, neither albuminuria nor glomerular filtration rate decline are diabetic nephropathyspecific markers, thus the diagnosis of diabetic nephropathy greatly depends on assumptions. several factors should be taken into account when urinary albumin levels are assessed before establishing the diagnosis of diabetic nephropathy, while newer more specific markers for diabetic nephropathy are urgently needed.
Hormones – Springer Journals
Published: Dec 30, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.