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Youth and long-term dietary calcium intake with risk of impaired glucose metabolism and type 2 diabetes in adulthood

Youth and long-term dietary calcium intake with risk of impaired glucose metabolism and type 2... Abstract Context No previous studies have examined the role of youth calcium intake in the development of impaired glucose metabolism, particularly those with long-term high calcium intake. Objectives To examine whether youth and long-term (between youth and adulthood) dietary calcium intake is associated with adult impaired glucose metabolism and T2D. Design, Setting, and Participants The Cardiovascular Risk in Young Finns Study (YFS) is a 31-year prospective cohort study (n=1134, aged 3-18 years at baseline). Exposures Dietary calcium intake was assessed at baseline (1980) and adult follow-ups (2001, 2007 and 2011). Long-term (mean between youth and adulthood) dietary calcium intake was calculated. Main outcome measures Adult impaired fasting glucose (IFG) and T2D. Results We found no evidence for non-linear associations between calcium intake with IFG or T2D among females and males (all p for non-linearity>0.05). Higher youth and long-term dietary calcium intake was not associated with the risk of IFG or T2D among females or males after adjustment for confounders including youth and adult BMI. Conclusions Youth or long-term dietary calcium intake is not associated with adult risk of developing impaired glucose metabolism or T2D. Copyright © 2019 Endocrine Society http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical Endocrinology and Metabolism Oxford University Press

Youth and long-term dietary calcium intake with risk of impaired glucose metabolism and type 2 diabetes in adulthood

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References (28)

Publisher
Oxford University Press
Copyright
Copyright © 2019 Endocrine Society
ISSN
0021-972X
eISSN
1945-7197
DOI
10.1210/jc.2018-02321
Publisher site
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Abstract

Abstract Context No previous studies have examined the role of youth calcium intake in the development of impaired glucose metabolism, particularly those with long-term high calcium intake. Objectives To examine whether youth and long-term (between youth and adulthood) dietary calcium intake is associated with adult impaired glucose metabolism and T2D. Design, Setting, and Participants The Cardiovascular Risk in Young Finns Study (YFS) is a 31-year prospective cohort study (n=1134, aged 3-18 years at baseline). Exposures Dietary calcium intake was assessed at baseline (1980) and adult follow-ups (2001, 2007 and 2011). Long-term (mean between youth and adulthood) dietary calcium intake was calculated. Main outcome measures Adult impaired fasting glucose (IFG) and T2D. Results We found no evidence for non-linear associations between calcium intake with IFG or T2D among females and males (all p for non-linearity>0.05). Higher youth and long-term dietary calcium intake was not associated with the risk of IFG or T2D among females or males after adjustment for confounders including youth and adult BMI. Conclusions Youth or long-term dietary calcium intake is not associated with adult risk of developing impaired glucose metabolism or T2D. Copyright © 2019 Endocrine Society

Journal

Journal of Clinical Endocrinology and Metabolism – Oxford University Press

Published: Jan 9, 2019

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