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Medical Letter Medical Letter Journal of Cutaneous Medicine and Surgery 2020, Vol. 24(2) 193–194 The Human Chorionic Gonadotropin © The Author(s) 2019 Article reuse guidelines: sagepub. com/ journals- permissions Diet: Elevated Pregnancy Markers in DOI: 10.1177/1203475419888865 jcms.sagepub.com Patients on Isotretinoin 1 1 Megan Sander and Michael Sander Because of the risk of teratogenicity secondary to systemic Many studies have demonstrated that beta- hCG is no retinoids, it is imperative that patients taking isotretinoin are more effective for weight loss than a calorie- restricted diet. Additionally, several studies have documented health risks aware of the risks of becoming pregnant. To monitor for associated with this diet. Reported adverse effects include pregnancy, most physicians will monitor beta- human chori- headache, fatigue, depression, hyperandrogenism, ascites, onic gonadotropin (beta-hCG) throughout treatment. pleural effusions, and thromboembolism. Since there is Recently, patients on isotretinoin have been noted to strong evidence that exogenous beta-hCG does not work as a have mildly elevated levels of beta-hCG. These levels weight loss aid, and since there are health concerns associ- have been between 8 and 10 IU/L (0-5 IU/L normal range). ated with its use, the administration of beta-hCG is not rec - On further questioning, these patients deny
Journal of Cutaneous Medicine and Surgery – SAGE
Published: Mar 1, 2020
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