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C. Gallistel, A. King, A. Daniel, D. Freestone, E. Papachristos, F. Balcı, A. Kheifets, J. Zhang, X. Su, G. Schiff, H. Kourtev (2010)
Screening for Learning and Memory Mutations: A New Approach.Xin li xue bao. Acta psychologica Sinica, 42 1
Anegon I.
Neurobehavioral tests in rat models of degenerative brain diseases
V. Tucci (2012)
Sleep, Circadian Rhythms, and Interval Timing: Evolutionary Strategies to Time InformationFrontiers in Integrative Neuroscience, 5
D. Shurtleff, T. Raslear, L. Simmons (1990)
Circadian variations in time perception in ratsPhysiology & Behavior, 47
Agostino P. V. Golombek D. A. Meck W. H.
Unwinding the molecular basis of interval and circadian timing
J. Crabbe, D. Wahlsten, B. Dudek (1999)
Genetics of mouse behavior: interactions with laboratory environment.Science, 284 5420
V. Tucci, H. Lad, A. Parker, Sian Polley, Steve Brown, P. Nolan (2006)
Gene-environment interactions differentially affect mouse strain behavioral parametersMammalian Genome, 17
C. Buhusi, W. Meck (2005)
What makes us tick? Functional and neural mechanisms of interval timingNature Reviews Neuroscience, 6
F. Balcı, D. Freestone, C. Gallistel (2009)
Risk assessment in man and mouseProceedings of the National Academy of Sciences, 106
K. Mekada, K. Abe, A. Murakami, Satoe Nakamura, Hatsumi Nakata, K. Moriwaki, Y. Obata, A. Yoshiki (2009)
Genetic differences among C57BL/6 substrains.Experimental animals, 58 2
D. Bailey (1978)
SOURCES OF SUBLINE DIVERGENCE AND THEIR RELATIVE IMPORTANCE FOR SUBLINES OF SIX MAJOR INBRED STRAINS OF MICE1
O. Stiedl, J. Radulovic, R. Lohmann, Karin Birkenfeld, Markki Palve, J. Kammermeier, F. Sananbenesi, J. Spiess (1999)
Strain and substrain differences in context- and tone-dependent fear conditioning of inbred miceBehavioural Brain Research, 104
S. Mandillo, V. Tucci, S. Hölter, H. Meziane, M. Banchaabouchi, M. Kallnik, H. Lad, P. Nolan, A. Ouagazzal, E. Coghill, K. Gale, E. Golini, S. Jacquot, W. Krężel, A. Parker, Fabrice Riet, Ilka Schneider, D. Marazziti, J. Auwerx, Steve Brown, P. Chambon, N. Rosenthal, G. Tocchini-Valentini, W. Wurst (2008)
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study.Physiological genomics, 34 3
V. Tucci, F. Achilli, G. Blanco, H. Lad, S. Wells, S. Godinho, P. Nolan (2007)
Reaching and grasping phenotypes in the mouse (Mus musculus): A characterization of inbred strains and mutant linesNeuroscience, 147
P. Agostino, Micaela Nascimento, Ivana Bussi, M. Eguia, D. Golombek (2011)
Circadian modulation of interval timing in miceBrain Research, 1370
F. Balcı, E. Papachristos, C. Gallistel, D. Brunner, J. Gibson, G. Shumyatsky (2008)
Interval timing in genetically modified mice: a simple paradigmGenes, 7
S. Godinho, E. Maywood, L. Shaw, V. Tucci, A. Barnard, L. Busino, M. Pagano, Rachel Kendall, M. Quwailid, M. Romero, J. O’Neill, J. Chesham, D. Brooker, Zuzanna Lalanne, M. Hastings, P. Nolan (2007)
The After-Hours Mutant Reveals a Role for Fbxl3 in Determining Mammalian Circadian PeriodScience, 316
R. Khisti, J. Wolstenholme, K. Shelton, M. Miles (2006)
Characterization of the ethanol-deprivation effect in substrains of C57BL/6 mice.Alcohol, 40 2
M. Ferrara, L. Gennaro, M. Bertini (2000)
Time-course of sleep inertia upon awakening from nighttime sleep with different sleep homeostasis conditions.Aviation, space, and environmental medicine, 71 3
A. Barnard, P. Nolan (2008)
When Clocks Go Bad: Neurobehavioural Consequences of Disrupted Circadian TimingPLoS Genetics, 4
K. Blum, A. Briggs, L. Delallo, Elston Sf, R. Ochoa (1982)
Whole brain methionine-enkephalin of ethanol-avoiding and ethanol-preferring C57BL miceExperientia, 38
Russell Church, Warren Meck, John Gibbon (1994)
Application of scalar timing theory to individual trials.Journal of experimental psychology. Animal behavior processes, 20 2
Behavioral Neuroscience
F. Balcı, D. Freestone, P. Simen, Laura deSouza, J. Cohen, P. Holmes (2011)
Optimal Temporal Risk AssessmentFrontiers in Integrative Neuroscience, 5
Matsuo N. Yamasaki N. Ohira K. Takao K. Toyama K. Eguchi M. Yamaguchi S. Miyakawa T.
Neural activity changes underlying the working memory deficit in alpha-CaMKII heterozygous knockout mice
Tassi P. Muzet A.
Sleep inertia
T. Leise, P. Indic, M. Paul, W. Schwartz (2013)
Wavelet Meets ActogramJournal of Biological Rhythms, 28
G. Lassi, S. Ball, S. Maggi, G. Colonna, T. Nieus, C. Cero, A. Bartolomucci, J. Peters, V. Tucci (2012)
Loss of Gnas Imprinting Differentially Affects REM/NREM Sleep and Cognition in MicePLoS Genetics, 8
M. Kas, J. Ree (2004)
Dissecting complex behaviours in the post-genomic eraTrends in Neurosciences, 27
F. Balcı, C. Gallistel, B. Allen, K. Frank, J. Gibson, D. Brunner (2009)
Acquisition of peak responding: What is learned?Behavioural Processes, 80
P. Agostino, D. Golombek, W. Meck, John Araujo, Olga Sysoeva, Washington
Integrative Neuroscience Review Article Unwinding the Molecular Basis of Interval and Circadian Timing
F. Balcı, P. Simen, R. Niyogi, Andrew Saxe, Jessica Hughes, P. Holmes, J. Cohen (2011)
Acquisition of decision making criteria: reward rate ultimately beats accuracyAttention, Perception, & Psychophysics, 73
J. Radulovic, J. Kammermeier, J. Spiess (1998)
Generalization of fear responses in C57BL/6N mice subjected to one-trial foreground contextual fear conditioningBehavioural Brain Research, 95
The Consortium (2005)
EMPReSS: standardized phenotype screens for functional annotation of the mouse genomeNature Genetics, 37
K. Cheng, Richard Westwood (1993)
Analysis of single trials in pigeons' timing performance.Journal of Experimental Psychology: Animal Behavior Processes, 19
Phenotyping behavioral and cognitive processes is a critical practice in mouse research and reliable phenotypic assessment is an essential component of building well-defined links between genes and behavioral/cognitive functions. The success of behavioral screens in neurobehavioral mouse genetics depends on the identification of reliable, reproducible, and high-throughput behavioral/cognitive measures from individual animals irrespective of the differences in opinions regarding how to tackle phenotyping in different behavioral domains. Furthermore, reliable behavioral assays must be resistant to inevitable environmental differences across laboratories since protocols can be replicated but not all the environmental conditions. Here we present a cross-laboratory study of interval timing behaviors in mice. Two classically used mouse inbred substrains, C57BL/6J and C57BL/6N, were studied over several days in home-cages containing automated testing apparatus. Remarkably, all timing measures in mouse performance showed a robust reproducibility across centers and even small differences between the two substrains were comparable across laboratories. Moreover, we have observed a consistent increase in error rate during the light phase of the light–dark cycle, which suggests that mouse performance during this phase is compromised by a possible sleep inertia-like effect. Overall, our study demonstrates that analysis of mouse timing behavior can lead to robust and reliable endophenotypes in mouse behavioral genetic studies.
Timing & Time Perception – Brill
Published: Jan 1, 2014
Keywords: Interval timing; mice; C57BL/6 substrains; home cages; endophenotypes; sleep inertia
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