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Clinical significance of simultaneous measurement of reticulated platelets and large platelets in idiopathic thrombocytopenic purpura

Clinical significance of simultaneous measurement of reticulated platelets and large platelets in... Haematologia , Vol. 30, No. 3, pp. 183 – 192 (2000) Ó VSP 2000. Paper Clinical significance of simultaneous measurement of reticulated platelets and large platelets in idiopathic thrombocytopenic purpura T. TAKUBO ∗ , T. YAMANE, M. HINO, K. OHTA, K. R. KOH and N. TATSUMI Department of Clinical and Laboratory Medicine, Osaka City University Medical School, 1-4-3, Asahimachi, Abeno-ku, Osaka 545-8585, Japan Abstract —Frequencies of reticulated platelets (RP) and large platelets (LP) among circulating platelets can now be simultaneously determined using the R-3000 automated reticulocyte counter (Sysmex, Kobe, Japan) equipped with special software. We measured frequencies of RP and LP in patients with idiopathic thrombocytopenic purpura (ITP, acute type n = 5; chronic type n = 39), and healthy normal controls ( n = 20). In ITP patients, the platelet-associated IgG (PAIgG) level was also determined. Both RP and LP were significantly higher in chronic ITP patients than those in normal volunteers, and interestingly, the LP in acute ITP was significantly lower than that in chronic ITP although there was no significant difference in RP between acute and chronic ITP. Furthermore, we analyzed the changes in both RP and LP during the clinical course of ITP to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Haematologia Brill

Clinical significance of simultaneous measurement of reticulated platelets and large platelets in idiopathic thrombocytopenic purpura

Yamane, T.; Koh, K. R.; Takubo, T.; Ohta, K.; Hino, M.; Tatsumi, N.
Haematologia , Volume 30 (3): 183 – Jan 1, 2000
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Publisher
Brill
Copyright
© 2000 Koninklijke Brill NV, Leiden, The Netherlands
ISSN
0017-6559
eISSN
1568-5594
DOI
10.1163/156855900300109189
Publisher site
See Article on Publisher Site

Abstract

Haematologia , Vol. 30, No. 3, pp. 183 – 192 (2000) Ó VSP 2000. Paper Clinical significance of simultaneous measurement of reticulated platelets and large platelets in idiopathic thrombocytopenic purpura T. TAKUBO ∗ , T. YAMANE, M. HINO, K. OHTA, K. R. KOH and N. TATSUMI Department of Clinical and Laboratory Medicine, Osaka City University Medical School, 1-4-3, Asahimachi, Abeno-ku, Osaka 545-8585, Japan Abstract —Frequencies of reticulated platelets (RP) and large platelets (LP) among circulating platelets can now be simultaneously determined using the R-3000 automated reticulocyte counter (Sysmex, Kobe, Japan) equipped with special software. We measured frequencies of RP and LP in patients with idiopathic thrombocytopenic purpura (ITP, acute type n = 5; chronic type n = 39), and healthy normal controls ( n = 20). In ITP patients, the platelet-associated IgG (PAIgG) level was also determined. Both RP and LP were significantly higher in chronic ITP patients than those in normal volunteers, and interestingly, the LP in acute ITP was significantly lower than that in chronic ITP although there was no significant difference in RP between acute and chronic ITP. Furthermore, we analyzed the changes in both RP and LP during the clinical course of ITP to

Journal

Haematologia – Brill

Published: Jan 1, 2000

Keywords: large platelets; idiopathic thrombocytopenic purpura; Reticulated platelets; R-3000 automated reticulocyte counter

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