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Interaction between tissues and implantable materials

Interaction between tissues and implantable materials Frontiers Med. Biol. Engng , Vol. 10, No. 2, pp. 79 – 82 (2000) Ó VSP 2000. Interaction between tissues and implantable materials MAŁGORZATA LEWANDOWSKA-SZUMIEŁ and JANUSZ KOMENDER The Medical University of Warsaw, Institute of Biostructure, Department of Transplantology & Central Tissue Bank, ul. Chałubi ´ nskiego 5, 02-004 Warsaw, Poland Received 9 October 1998; accepted 30 March 1999 Abstract —Interaction between tissues and implantable materials is a factor of critical importance in biocompatibility studies. Bioactivity of implants is expected when the resorption or controlled integration of the implant with surrounding tissues is required. On the contrary, biomaterial inertness is suitable in the case of most load-bearing implants. Both desired and undesired consequences of partial implant biodegradation are discussed on the base of the authors’ experimental work done on alumina and carbon-fiber-reinforced carbon composites (CFRC). Two examples of investigations of the interaction between bioceramics (CFRC, alumina, hydroxyapatite, and tricalcium phosphate) and cells in culture are shown as an alternative to the methods based on experimental implantation. The future of research on biomaterial – tissue interaction is discussed with respect to the developments in tissue engineering. Key words : Biomaterials; bioceramics; biocompatibility; bioactivity; tissue engineering; alumina; carbon; hydroxyapatite; tricalcium http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Frontiers of Medical & Biological Engineering Brill

Interaction between tissues and implantable materials

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Publisher
Brill
Copyright
© 2000 Koninklijke Brill NV, Leiden, The Netherlands
ISSN
0921-3775
eISSN
1568-5578
DOI
10.1163/15685570052061937
Publisher site
See Article on Publisher Site

Abstract

Frontiers Med. Biol. Engng , Vol. 10, No. 2, pp. 79 – 82 (2000) Ó VSP 2000. Interaction between tissues and implantable materials MAŁGORZATA LEWANDOWSKA-SZUMIEŁ and JANUSZ KOMENDER The Medical University of Warsaw, Institute of Biostructure, Department of Transplantology & Central Tissue Bank, ul. Chałubi ´ nskiego 5, 02-004 Warsaw, Poland Received 9 October 1998; accepted 30 March 1999 Abstract —Interaction between tissues and implantable materials is a factor of critical importance in biocompatibility studies. Bioactivity of implants is expected when the resorption or controlled integration of the implant with surrounding tissues is required. On the contrary, biomaterial inertness is suitable in the case of most load-bearing implants. Both desired and undesired consequences of partial implant biodegradation are discussed on the base of the authors’ experimental work done on alumina and carbon-fiber-reinforced carbon composites (CFRC). Two examples of investigations of the interaction between bioceramics (CFRC, alumina, hydroxyapatite, and tricalcium phosphate) and cells in culture are shown as an alternative to the methods based on experimental implantation. The future of research on biomaterial – tissue interaction is discussed with respect to the developments in tissue engineering. Key words : Biomaterials; bioceramics; biocompatibility; bioactivity; tissue engineering; alumina; carbon; hydroxyapatite; tricalcium

Journal

Frontiers of Medical & Biological Engineering – Brill

Published: Jan 1, 2000

Keywords: bioceramics; bioactivity; hydroxyapatite; Biomaterials; alumina; biocompatibility; tissue engineering; carbon; tricalcium phosphate

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