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Soft Tissue B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Burkitt's Lymphoma Diagnosed by Fine Needle Aspiration Cytology

Soft Tissue B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large... Dear Editor,We present a case of B-cell lymphoma, unclassifiable (B-UNC), with features intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt's lymphoma (BL). The B-UNC/BL/DLBCL type belongs to the heterogeneous category that does neither meet the criteria for classical BL nor for DLBCL, and it is usually characterized by complex karyotypes, aggressive behavior and a poor prognosis [1,2,3,4].An 81-year-old male had a 3-month history of severe pain and slight thickness in the left thoracic paravertebral region (fig. 1a). His symptoms were initially misdiagnosed as degenerative thoracic kyphoscoliosis which was treated with physical therapy. Since the pain did not diminish, he was sent for an ultrasound (US) examination and a fine needle aspiration (FNA) analysis of the described lesion. A cytological analysis revealed only a few scattered atypical medium-sized lymphatic cells and peripheral blood; therefore, additional samples were taken. A psychical examination was also performed. In addition, an enlarged lymph node was found in the right axilla, from which samples were taken. Cytomorphological findings were as follows: a mixed cell population of lymphoid cells consisting mainly of centroblasts with dark blue cytoplasm and cytoplasmic vacuoles, as well as some centrocytes and immunoblasts. A small number of cells had nuclear morphological http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Cytologica Karger

Soft Tissue B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Burkitt's Lymphoma Diagnosed by Fine Needle Aspiration Cytology

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Publisher
Karger
Copyright
© 2015 S. Karger AG, Basel
ISSN
0001-5547
eISSN
1938-2650
DOI
10.1159/000438816
Publisher site
See Article on Publisher Site

Abstract

Dear Editor,We present a case of B-cell lymphoma, unclassifiable (B-UNC), with features intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt's lymphoma (BL). The B-UNC/BL/DLBCL type belongs to the heterogeneous category that does neither meet the criteria for classical BL nor for DLBCL, and it is usually characterized by complex karyotypes, aggressive behavior and a poor prognosis [1,2,3,4].An 81-year-old male had a 3-month history of severe pain and slight thickness in the left thoracic paravertebral region (fig. 1a). His symptoms were initially misdiagnosed as degenerative thoracic kyphoscoliosis which was treated with physical therapy. Since the pain did not diminish, he was sent for an ultrasound (US) examination and a fine needle aspiration (FNA) analysis of the described lesion. A cytological analysis revealed only a few scattered atypical medium-sized lymphatic cells and peripheral blood; therefore, additional samples were taken. A psychical examination was also performed. In addition, an enlarged lymph node was found in the right axilla, from which samples were taken. Cytomorphological findings were as follows: a mixed cell population of lymphoid cells consisting mainly of centroblasts with dark blue cytoplasm and cytoplasmic vacuoles, as well as some centrocytes and immunoblasts. A small number of cells had nuclear morphological

Journal

Acta Cytologica – Karger

Published: Jan 1, 2015

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