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Development of JAK2V617F-Positive Polycythemia Vera after Chemotherapy-Induced Remission of Primary Central Nervous System Diffuse Large B Cell Non-Hodgkin's Lymphoma: A Case Report and Review of the Literature

Development of JAK2V617F-Positive Polycythemia Vera after Chemotherapy-Induced Remission of... The coexistence or the development of Philadelphia chromosome-negative myeloproliferative neoplasms after a lymphoproliferative disease in the same patient is an extremely rare event. We report the case of a 72-year-old man who developed JAK2V617F polycythemia vera 3 years after the diagnosis and treatment of primary diffuse large B cell non-Hodgkin's lymphoma of the central nervous system. We also review the literature regarding the pathogenesis underlying the association of myeloproliferative and lymphoproliferative chronic disorders. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Haematologica Karger

Development of JAK2V617F-Positive Polycythemia Vera after Chemotherapy-Induced Remission of Primary Central Nervous System Diffuse Large B Cell Non-Hodgkin's Lymphoma: A Case Report and Review of the Literature

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References (21)

Publisher
Karger
Copyright
© 2013 S. Karger AG, Basel
ISSN
0001-5792
eISSN
1421-9662
DOI
10.1159/000347159
Publisher site
See Article on Publisher Site

Abstract

The coexistence or the development of Philadelphia chromosome-negative myeloproliferative neoplasms after a lymphoproliferative disease in the same patient is an extremely rare event. We report the case of a 72-year-old man who developed JAK2V617F polycythemia vera 3 years after the diagnosis and treatment of primary diffuse large B cell non-Hodgkin's lymphoma of the central nervous system. We also review the literature regarding the pathogenesis underlying the association of myeloproliferative and lymphoproliferative chronic disorders.

Journal

Acta HaematologicaKarger

Published: Jan 1, 2013

Keywords: Myeloproliferative neoplasms; Lymphoproliferative chronic disorders; Primary central nervous system lymphoma

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